Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Methylglyoxal (MGO) is the organic compound with the formula CH3C(O)CHO. It is a reduced derivative of pyruvic acid. It is a reactive compound that is implicated in the biology of diabetes. Methylglyoxal is produced industrially by degradation of carbohydrates using overexpressed methylglyoxal synthase.[1]
^Lichtenthaler, Frieder W. (2010). "Carbohydrates as Organic Raw Materials". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.n05_n07. ISBN 978-3527306732.
diabetes. Methylglyoxal is produced industrially by degradation of carbohydrates using overexpressed methylglyoxal synthase. Gaseous methylglyoxal has two...
The methylglyoxal pathway is an offshoot of glycolysis found in some prokaryotes, which converts glucose into methylglyoxal and then into pyruvate. However...
spontaneous reaction between a glutathionyl group and aldehydes such as methylglyoxal. (R)-S-lactoylglutathione = glutathione + 2-oxopropanal Glyoxalase I...
glyoxalase system is a set of enzymes that carry out the detoxification of methylglyoxal and the other reactive aldehydes that are produced as a normal part...
the synthesis of fluorocitrate from fluoroacetate or the synthesis of methylglyoxal from glycerol. The term was first publicised by Rudolph Peters in his...
glycation applies to DNA damage induced by reactive carbonyls (principally methylglyoxal and glyoxal) that are present in cells as by-products of sugar metabolism...
Aminoacetone is a metabolite that is implicated in the biosynthesis of methylglyoxal. Aminoacetone is also produced during catabolism of the amino acid threonine...
→ GSSR + H2O Glutathione is also employed for the detoxification of methylglyoxal and formaldehyde, toxic metabolites produced under oxidative stress...
Lactaldehyde is an intermediate in the methylglyoxal metabolic pathway. Methylglyoxal is converted to D-lactaldehyde by glycerol dehydrogenase (gldA)....
concentrations is taken up by the liver and undergoes detoxification through the methylglyoxal pathway which ends with lactate. Acetoacetate in high concentrations...
large family of 1,2-diketones. A well-known compound of this class is methylglyoxal, CH3C(O)CHO, also known as pyruvaldehyde. These compounds are also known...
Mitoguazone (also known as methylglyoxal bis(guanylhydrazone) or MGBG) is a drug used in chemotherapy. Hoffmann H, Gutsche W, Amlacher R, Schulze W, Werner...
sequesters the reactive enediol intermediate to prevent decomposition to methylglyoxal and inorganic phosphate. The hydrogen bond between the enzyme and the...
C11H18N4O3. It is an advanced glycation end-product formed from arginine and methylglyoxal through the Maillard reaction. Argpyrimidine has been studied for its...
compound that is formed by the oxidation of glycine and is a precursor of methylglyoxal. It is a pathognomonic compound found in the urine of patients with...
glycation end-products pentosidine, carboxymethyllysine (CML), and methylglyoxal (MGO). Phenolic content in wine Proanthocyanidin-B2 on liberherbarum...
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