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Peroxynitrite information


Peroxynitrite

Chemical structure of the peroxynitrite anion
Names
IUPAC name
Oxido nitrite
Identifiers
CAS Number
  • 19059-14-4
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:25941
KEGG
  • C16845
PubChem CID
  • 104806
UNII
  • UR67NH4U77 checkY
CompTox Dashboard (EPA)
  • DTXSID10172540 Edit this at Wikidata
InChI
  • InChI=1S/HNO3/c2-1-4-3/h3H/p-1
    Key: CMFNMSMUKZHDEY-UHFFFAOYSA-M
SMILES
  • N(=O)O[O-]
Properties
Chemical formula
NO3
Molar mass 62.005 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Reactions of peroxynitrite leading to either apoptotic or necrotic cell death

Peroxynitrite (sometimes called peroxonitrite) is an ion with the formula ONOO. It is a structural isomer of nitrate, NO
3

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Peroxynitrite

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Peroxynitrite (sometimes called peroxonitrite) is an ion with the formula ONOO−. It is a structural isomer of nitrate, NO− 3 Peroxynitrite can be prepared...

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Reactive nitrogen species

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(•NO) with superoxide (O2•−) to form peroxynitrite (ONOO−): •NO (nitric oxide) + O2•− (superoxide) → ONOO− (peroxynitrite) Superoxide anion (O2−) is a reactive...

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Nitrotyrosine

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of tyrosine nitration mediated by reactive nitrogen species such as peroxynitrite anion and nitrogen dioxide. Nitrotyrosine is identified as an indicator...

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Oxidative stress

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(•O− 2), nitric oxide (•NO) and their particularly reactive product, peroxynitrite (ONOO-). Although the use of these highly reactive compounds in the...

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Respiratory burst

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4H2O + 3NADP+ Nitric oxide may react with superoxide anions to produce peroxynitrite anion. O2•− + NO• → ONO2− The exposure to these reactive species in...

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Inosine

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natural antioxidant and peroxynitrite scavenger with potential benefits to patients with multiple sclerosis (MS). Peroxynitrite has been correlated with...

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Peroxynitric acid

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base of peroxynitric acid, is formed rapidly during decomposition of peroxynitrite in neutral conditions. Peroxynitric acid is formed in the atmosphere...

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Human serum albumin

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OH), hydrogen peroxide (H2O2) and the reactive nitrogen species as peroxynitrite (ONOO.), and have been shown to oxidize Cys34 to sulfenic acid derivate...

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Nitrogen oxide

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Nitroxide O=N− or NO− Nitrite O=N−O− or NO−2 Nitrate O2N−O− or NO−3 Peroxynitrite O=N−O−O− or NO−3 Peroxynitrate O2N−O−O− or NO−4 Orthonitrate +N(−O−)4...

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Potassium superoxide

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Sagan, Elisabeth S. (2004). Tetramethylammonium Salts of Superoxide and Peroxynitrite. Inorganic Syntheses. p. 36. doi:10.1002/0471653683.ch1. Haymaker, Webb;...

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Jacquin Niles

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Steven R. (1999). "The chemistry of DNA damage from nitric oxide and peroxynitrite". Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis...

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Cytochrome c

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made through the reaction of nitric oxide and superoxide. Presence of peroxynitrite or H2O2 and nitrogen dioxide NO2 in the mitochondria can be lethal since...

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Air purifier

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radical, Singlet Oxygen (dioxidene), Superoxide, Atomic Oxygen, Peroxynitrite (peroxynitrite). The two long-lived ROS ones are Hydrogen Peroxide – Gas Phased...

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Nitrate radical

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uncharged counterpart of the nitrate anion NO− 3 and an isomer of the peroxynitrite radical OONO. Nitrogen trioxide is an important intermediate in reactions...

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Tetrahydrobiopterin

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BH3 radical from reacting with other free radicals (superoxide and peroxynitrite specifically). Without this recycling process, uncoupling of the endothelial...

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Antioxidant

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react with some oxidants, such as superoxide, but does act against peroxynitrite, peroxides, and hypochlorous acid. Concerns over elevated UA's contribution...

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Nitric oxide

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Oxide, Part D: Oxide Detection, Mitochondria and Cell Functions, and Peroxynitrite Reactions. Methods in Enzymology. Vol. 359. pp. 27–42. doi:10...

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Dmitry Gabrilovich

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tumor cells can go through a mechanism that produces a free radical peroxynitrite, causing them to become resistant to certain types of cancer immunotherapy...

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Oxyacid

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+3 HNO 2 Nitrous acid NO− 2 Nitrite HOONO Peroxynitrous acid OONO− Peroxynitrite +2 H 2NO 2 Nitroxylic acid NO2− 2 Nitroxylate +1 H 2N 2O 2 Hyponitrous...

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Xanthine oxidase

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to nitric oxide (NO), which reacts with a superoxide anion to form peroxynitrite under aerobic conditions. XO has also been found to produce the strong...

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Reactive oxygen species

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reactive as these species, but is readily activated and is thus included. Peroxynitrite and nitric oxide are reactive oxygen-containing species as well. Hydroxyl...

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PRDX5

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cytosolic or mitochondrial thioredoxins to reduce alkyl hydroperoxides or peroxynitrite with high rate constants in the 106 to 107 M−1s−1 range, whereas its...

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Peroxiredoxin

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peroxides, specifically hydrogen peroxide, alkyl hydroperoxides, and peroxynitrite. Prxs were historically divided into three (mechanistic) classes: Typical...

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Superoxide dismutase

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targets. For example, it reacts with the NO radical, and makes toxic peroxynitrite. Because the uncatalysed dismutation reaction for superoxide requires...

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Carbon monoxide poisoning

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of nitric oxide, and the formation of oxygen free radicals including peroxynitrite. In the brain this causes further mitochondrial dysfunction, capillary...

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Sodium diethyldithiocarbamate

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Oxide, Part D: Oxide Detection, Mitochondria and Cell Functions, and Peroxynitrite Reactions. Methods in Enzymology. Vol. 359. pp. 27–42. doi:10...

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