Dopamine-releasing portion of the substantia nigra
"SNpc" redirects here. For the petroleum company, see Société Nationale des Pétroles du Congo.
Pars compacta
Details
Part of
substantia nigra
Identifiers
Latin
pars compacta substantiae nigrae
Acronym(s)
SNpc
MeSH
D065842
NeuroLex ID
birnlex_990
TA98
A14.1.06.112
TA2
5882
FMA
62907
Anatomical terms of neuroanatomy
[edit on Wikidata]
The pars compacta (SNpc) is one of two subdivisions of the substantia nigra of the midbrain (the other being the pars reticulata); it is situated medial to the pars reticulata. It is formed by dopaminergic neurons.[1] It projects to the striatum and portions of the cerebral cortex.[2] It is functionally involved in fine motor control.
Parkinson's disease is characterized by the death of dopaminergic neurons in this region.[1]
^ abKim, S. J.; Sung, JY; Um, JW; Hattori, N; Mizuno, Y; Tanaka, K; Paik, SR; Kim, J; Chung, KC (2003). "Parkin Cleaves Intracellular -Synuclein Inclusions via the Activation of Calpain". Journal of Biological Chemistry. 278 (43): 41890–9. doi:10.1074/jbc.M306017200. PMID 12917442.
^Martin, John D. (2020). Neuroanatomy: Text and Atlas (5th ed.). New York: McGraw Hill. p. 309. ISBN 978-1-259-64248-7.
The parscompacta (SNpc) is one of two subdivisions of the substantia nigra of the midbrain (the other being the pars reticulata); it is situated medial...
different connections and functions: the parscompacta (SNpc) and the pars reticulata (SNpr). The parscompacta serves mainly as a projection to the basal...
The pars reticulata (SNpr) is a portion of the substantia nigra and is located lateral to the parscompacta. Most of the neurons that project out of the...
hemisphere. It has two distinct parts, the parscompacta (SNc) and the pars reticulata (SNr). The parscompacta contains dopaminergic neurons from the A9...
made up of two parts, the parscompacta (SNpc) and the pars reticulata (SNpr), sometimes there is a reference to the pars lateralis but that is usually...
matter portion of the basal ganglia that has two parts – the parscompacta (SNc) and the pars reticulata (SNr). SNr often works in unison with GPi, and the...
large quantities in catecholaminergic cells of the substantia nigra parscompacta and locus coeruleus, giving a dark color to the structures. Neuromelanin...
set Parscompacta, a portion of the substantia nigra in anatomy Compactum This disambiguation page lists articles associated with the title Compacta. If...
individuals. The dopaminergic pathways that project from the substantia nigra parscompacta (SNc) and ventral tegmental area (VTA) into the striatum (i.e., the...
area called the parscompacta and an output area the pars reticulata. The dopaminergic neurons are found mainly in the parscompacta (cell group A8) and...
peduncle. It has two divisions of subnuclei; the parscompacta, containing mainly cholinergic neurons, and the pars dissipata, containing mainly glutamatergic...
substantia nigra contains two parts: the substantia nigra parscompacta (SNpc) and the substantia nigra pars reticulata (SNpr). The SNpc obtains input from the...
animals by lesioning the dopaminergic neurons of the substantia nigra parscompacta, in order to develop and test new medicines and treatments for Parkinson's...
nigrostriatal connection arising from the neurons of the substantia nigra parscompacta. While cortical axons synapse mainly on spine heads of spiny neurons...
pallidal nuclei and the two parts of the substantia nigra (the parscompacta and pars reticulata) constitute a high-frequency autonomous pacemaker. (see...
neuromodulatory inputs, notably dopaminergic axons from the substantia nigra parscompacta. It also receives inputs from the pedunculopontine nucleus. The axons...
nigra – one where neurons are densely packed (the parscompacta) and one where they are not (the pars reticulata), which serve a different role from one...
anti-inflammatory function. Conductive atomic force microscopy of substantia nigra parscompacta (SNc) tissue demonstrated evidence of electron tunneling between ferritin...
sends a descending tract to the lower motor neurons. Substantia nigra parscompacta: This is a concentration of neurons in the ventral portion of the midbrain...
synthesized by nuclei located in the mesencephalon. The substantia nigra parscompacta (SNpc), the ventral tegmental area (VTA) and the retrorubral field (RRF)...
linear nucleus of the raphe Interfascicular nucleus Substantia nigra ParscompactaPars reticulata Interpeduncular nucleus Cerebral peduncle Crus cerebri...
innervated by dopaminergic neurons that originate from the substantia nigra parscompacta (SNc). The SNc is located in the midbrain and contains cell projections...
patterns in the adult mouse show high expression in the substantia nigra parscompacta. DAT in the mesocortical pathway, labeled with radioactive antibodies...
observed experimentally, such as electron tunneling in substantia nigra parscompacta (SNc) tissue and the presence of disordered arrays of ferritin in SNc...
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