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Oxidopamine information


Oxidopamine
Names
Preferred IUPAC name
5-(2-Aminoethyl)benzene-1,2,4-triol
Identifiers
CAS Number
  • 1199-18-4 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:78741 checkY
ChEMBL
  • ChEMBL337702 checkY
ChemSpider
  • 4463 checkY
ECHA InfoCard 100.013.493 Edit this at Wikidata
EC Number
  • 214-842-3
KEGG
  • D05294 checkY
PubChem CID
  • 4624
UNII
  • 8HW4YBZ748 ☒N
CompTox Dashboard (EPA)
  • DTXSID0036768 Edit this at Wikidata
InChI
  • InChI=1S/C8H11NO3/c9-2-1-5-3-7(11)8(12)4-6(5)10/h3-4,10-12H,1-2,9H2 checkY
    Key: DIVDFFZHCJEHGG-UHFFFAOYSA-N checkY
  • InChI=1/C8H11NO3/c9-2-1-5-3-7(11)8(12)4-6(5)10/h3-4,10-12H,1-2,9H2
    Key: DIVDFFZHCJEHGG-UHFFFAOYAG
SMILES
  • c1c(c(cc(c1O)O)O)CCN
Properties
Chemical formula
C8H11NO3
Molar mass 169.18 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a neurotoxic synthetic organic compound used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain.

The main use for oxidopamine in scientific research is to induce Parkinsonism in laboratory animals by lesioning the dopaminergic neurons of the substantia nigra pars compacta, in order to develop and test new medicines and treatments for Parkinson's disease.

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Oxidopamine

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Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a neurotoxic synthetic organic compound used by researchers...

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MDMA

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neurotoxins Adrenergic DSP-4 Oxidopamine (6-OHDA) Dopaminergic Fenpropathrin Methamphetamine MPP+ MPTP Norsalsolinol Oxidopamine (6-OHDA) Rotenone Salsolinol...

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Salsolinol

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C8H11NO3

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exact mass: 169.073893 u) may refer to: Norepinephrine, or noradrenaline Oxidopamine, a dopamine derivative Pyridoxine This set index page lists chemical...

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Methamphetamine

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neurotoxins Adrenergic DSP-4 Oxidopamine (6-OHDA) Dopaminergic Fenpropathrin Methamphetamine MPP+ MPTP Norsalsolinol Oxidopamine (6-OHDA) Rotenone Salsolinol...

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MPTP

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Norsalsolinol

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Substituted phenethylamine

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OH β,4-dihydroxyphenethylamine Trace aminergic α-adrenoceptor agonist Oxidopamine OH OH OH 2,4,5-trihydroxyphenethylamine neurotoxic agent for the dopamine...

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Rotenone

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neurotoxins Adrenergic DSP-4 Oxidopamine (6-OHDA) Dopaminergic Fenpropathrin Methamphetamine MPP+ MPTP Norsalsolinol Oxidopamine (6-OHDA) Rotenone Salsolinol...

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List of dopaminergic drugs

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(BPAP) • Phenylpropylaminopentane (PPAP) • Selegiline (L-deprenyl) Oxidopamine (6-hydroxydopamine) XP21279 A photoswitchable agonist of D1-like receptors...

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Hydroxydopamine

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to: 2-Hydroxydopamine 5-Hydroxydopamine [Wikidata] 6-Hydroxydopamine (oxidopamine) This set index article lists chemical compounds articles associated...

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List of adrenergic drugs

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Bethanidine Bretylium Guanadrel Guanazodine Guanclofine Guanethidine Guanoxan Oxidopamine (6-hydroxydopamine) Prischich, Davia; Gomila, Alexandre M. J.; Milla-Navarro...

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Fenpropathrin

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Trifluoromethylaminoindane

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Omigapil

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progressive motor neuronopathy, MPTP-induced nigrostriatal degeneration, and oxidopamine-induced neuronal injury. Omigapil also prevents the death of nigrostriatal...

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