Ornithine aminotransferase (OAT) is an enzyme which is encoded in human by the OAT gene located on chromosome 10.
The OAT involved in the ultimate formation of the non-essential amino acid proline from the amino acid ornithine. Ornithine aminotransferase forms the initial intermediate in this process. It catalyzes the reverse reaction as well, and is therefore essential in creating ornithine from the starting substrate proline.
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Ornithineaminotransferase (OAT) is an enzyme which is encoded in human by the OAT gene located on chromosome 10. The OAT involved in the ultimate formation...
Ornithineaminotransferase deficiency (also known as gyrate atrophy of the choroid and retina) is an inborn error of ornithine metabolism, caused by decreased...
deficiency, but can also be seen in neonatal presentations of ornithineaminotransferase deficiency. Only severely affected males consistently demonstrate...
creatine can be obtained from dietary sources or supplementation. Ornithineaminotransferase deficiency can cause secondary creatine deficiency, however it...
where it is a cofactor of GABA aminotransferase. Metabolism of ornithine. Pyridoxal phosphate is a cofactor of ornithine carboxylase. Transamination. Pyridoxal...
(using NADH or NADPH), or turned into ornithine by ornithineaminotransferase, followed by cyclisation by ornithine cyclodeaminase to form proline. Proline...
(using NADH or NADPH), or turned into ornithine by ornithineaminotransferase, followed by cyclisation by ornithine cyclodeaminase to form proline. L-Proline...
is N2-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase. Other names in common use include succinylornithine aminotransferase, N2-succinylornithine...
enzymes. It inhibits ornithineaminotransferase at concentrations as low as 10 nM. l-Canaline is a substrate for ornithineaminotransferase resulting in the...
into ornithine by ornithineaminotransferase, followed by cyclisation by ornithine cyclodeaminase to form proline. Citrulline is made from ornithine and...
delta-1-pyrroline-5-carboxylate synthase. Ornithineaminotransferase is an enzyme that converts arginine and ornithine into glutamate and GABA. Both of these...
aminotransferase and yield the N-acetyl-L-ornithine. The acetyl group of acetylornithine is removed by the enzyme acetylornithinase (AO) or ornithine...
synthetase I. The second step facilitated by ornithine transcarbamylase converts carbamoyl phosphate and ornithine into citrulline. After these initial steps...
group of the newly formed glutamate is transferred to pyruvate by an aminotransferase enzyme, regenerating the α-ketoglutarate, and converting the pyruvate...
function tests, including elevated aspartate aminotransferase (59%), elevated alanine aminotransferase (46%), and elevated total blood bilirubin (27%)...
on, four pathway variations have been found, namely the acetylase, aminotransferase, dehydrogenase, and succinylase pathways. Both the acetylase and succinylase...
metabolism is initially catalyzed by the branched-chain amino acid aminotransferase enzyme, producing α-ketoisocaproate (α-KIC). α-KIC is mostly metabolized...
intermediates in the metabolic pathways for standard amino acids – for example, ornithine and citrulline occur in the urea cycle, part of amino acid catabolism...
Acetohydroxy acid isomeroreductase Dihydroxyacid dehydratase Valine aminotransferase Isoleucine is both a glucogenic and a ketogenic amino acid. After transamination...
Acetohydroxy acid isomeroreductase Dihydroxyacid dehydratase Valine aminotransferase Like other branched-chain amino acids, the catabolism of valine starts...
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