Arginine and proline metabolism is one of the central pathways for the biosynthesis of the amino acids arginine and proline from glutamate. The pathways linking arginine, glutamate, and proline are bidirectional. Thus, the net utilization or production of these amino acids is highly dependent on cell type and developmental stage.
Altered proline metabolism has been linked to metastasis formation in breast cancer.[1]
^Elia, Ilaria; Broekaert, Dorien; Christen, Stefan; Boon, Ruben; Radaelli, Enrico; Orth, Martin F.; Verfaillie, Catherine; Grünewald, Thomas G. P.; Fendt, Sarah-Maria (2017). "Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells". Nature Communications. 8: 15267. Bibcode:2017NatCo...815267E. doi:10.1038/ncomms15267. PMC 5437289. PMID 28492237.
and 19 Related for: Arginine and proline metabolism information
in arginineandprolinemetabolism. This enzyme is widely expressed in bacteria, including streptococcus and actinomyces. The bacterial arginine deiminase...
This enzyme participates in arginineandprolinemetabolism. The systematic name of this enzyme class is ATP:L-arginine Nω-phosphotransferase Other names...
Carbohydrate metabolism is the whole of the biochemical processes responsible for the metabolic formation, breakdown, and interconversion of carbohydrates...
is proline racemase. This enzyme participates in arginineandprolinemetabolism. These enzymes catalyse the interconversion of L- and D-proline in bacteria...
also called creatinine hydrolase. This enzyme participates in arginineandprolinemetabolism. Creatininase from Pseudomonas putida has a core structure...
linking arginine, glutamine, andproline are bidirectional. Thus, the net use or production of these amino acids is highly dependent on cell type and developmental...
and is catalyzed by argininosuccinate synthetase. Argininosuccinate undergoes cleavage by argininosuccinase to form arginineand fumarate. Arginine is...
found in the study's urine samples. The disruption of the arginine andprolinemetabolism associated with this elevated MnBP concentration as a result of...
Protein metabolism denotes the various biochemical processes responsible for the synthesis of proteins and amino acids (anabolism), and the breakdown...
Lipid metabolism is the synthesis and degradation of lipids in cells, involving the breakdown and storage of fats for energy and the synthesis of structural...
Metabolism (/məˈtæbəlɪzəm/, from Greek: μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms. The three main functions...
proline can be synthesized from diethyl malonate and acrylonitrile: Hyperprolinemia Inborn error of metabolism Prolidase deficiency Prolinol "Proline"...
also called glycocyamine kinase. This enzyme participates in arginineandprolinemetabolism. HOBSON GE, REES KR (1957). "The annelid phosphokinases". Biochem...
N2-succinylglutamate desuccinylase, SGDS, and AstE. This enzyme participates in arginineandprolinemetabolism. Vander Wauven C, Stalon V (1985). "Occurrence...
use include creatinine hydrolase, and creatinine desiminase. This enzyme participates in arginineandprolinemetabolism. Szulmajster J (October 1958). "Bacterial...