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Valine information


Valine
Skeletal formula of neutral valine
Zwitterionic valine
Ball-and-stick model
Space-filling model
Names
IUPAC name
Valine
Other names
2-Amino-3-methylbutanoic acid
2-Aminoisovaleric acid
Valic acid
Identifiers
CAS Number
  • L: 72-18-4 checkY
  • D/L: 516-06-3 checkY
  • D: 640-68-6 checkY
3D model (JSmol)
  • L: Interactive image
  • L Zwitterion: Interactive image
ChEBI
  • L: CHEBI:16414 checkY
ChEMBL
  • L: ChEMBL43068 checkY
ChemSpider
  • L: 6050 checkY
  • D/L: 1148 checkY
  • D: 64635 checkY
DrugBank
  • L: DB00161 checkY
ECHA InfoCard 100.000.703 Edit this at Wikidata
EC Number
  • L: 200-773-6
IUPHAR/BPS
  • L: 4794
KEGG
  • L: D00039 checkY
PubChem CID
  • L: 6287
  • D/L: 1182
  • D: 71563
UNII
  • L: HG18B9YRS7 checkY
  • D/L: 4CA13A832H checkY
  • D: Y14I1443UR checkY
CompTox Dashboard (EPA)
  • L: DTXSID40883233 Edit this at Wikidata
InChI
  • InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1 checkY
    Key: KZSNJWFQEVHDMF-BYPYZUCNSA-N checkY
  • D/L: Key: KZSNJWFQEVHDMF-UHFFFAOYSA-N
  • D: Key: KZSNJWFQEVHDMF-SCSAIBSYSA-N
SMILES
  • L: CC(C)[C@@H](C(=O)O)N
  • L Zwitterion: CC(C)[C@@H](C(=O)[O-])[NH3+]
Properties[3]
Chemical formula
C5H11NO2
Molar mass 117.148 g·mol−1
Density 1.316 g/cm3
Melting point 298 °C (568 °F; 571 K) (decomposition)
Solubility in water
soluble, 85 g/L [1]
Acidity (pKa) 2.32 (carboxyl), 9.62 (amino)[2]
Magnetic susceptibility (χ)
-74.3·10−6 cm3/mol
Supplementary data page
Valine (data page)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Valine (symbol Val or V)[4] is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH3+ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO form under biological conditions), and a side chain isopropyl group, making it a non-polar aliphatic amino acid. Valine is essential in humans, meaning the body cannot synthesize it; it must be obtained from dietary sources which are foods that contain proteins, such as meats, dairy products, soy products, beans and legumes. It is encoded by all codons starting with GU (GUU, GUC, GUA, and GUG).

  1. ^ "Physicochemical Information". emdmillipore. 2022. Retrieved 17 November 2022.
  2. ^ Dawson RM, Elliott DC, Elliott WH, Jones KM, eds. (1959). Data for Biochemical Research. Oxford: Clarendon Press. ASIN B000S6TFHA. OCLC 859821178.
  3. ^ Weast RC, ed. (1981). CRC Handbook of Chemistry and Physics (62nd ed.). Boca Raton, FL: CRC Press. p. C-569. ISBN 0-8493-0462-8.
  4. ^ "Nomenclature and Symbolism for Amino Acids and Peptides". IUPAC-IUB Joint Commission on Biochemical Nomenclature. 1983. Archived from the original on 9 October 2008. Retrieved 5 March 2018.

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Valine

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Valine (symbol Val or V) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH3+...

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Valine decarboxylase

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In enzymology, a valine decarboxylase (EC 4.1.1.14) is an enzyme that catalyzes the chemical reaction L-valine ⇌ {\displaystyle \rightleftharpoons } 2-methylpropanamine...

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Amino acid synthesis

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transamination catalyzed either by an alanine-valine transaminase or a glutamate-valine transaminase. Valine biosynthesis is subject to feedback inhibition...

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Valines

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Valines (French pronunciation: [valin]) is a commune in the Somme department in Hauts-de-France in northern France. Valines is situated 9 miles (14 km)...

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ACV synthetase

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(ACVS, L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase, N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase, EC 6.3.2.26) is an enzyme that...

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Essential amino acid

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common to all life forms, the nine amino acids humans cannot synthesize are valine, isoleucine, leucine, methionine, phenylalanine, tryptophan, threonine,...

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Maple syrup urine disease

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is essential for breaking down the amino acids leucine, isoleucine, and valine. These are present in some quantity in almost all kinds of food, but in...

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Isobutylamine

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the decarboxylated form of the amino acid valine, and the product of the metabolism thereof by the enzyme valine decarboxylase. Isobutylamine is an odorant...

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Alkanolamine

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is a precursor to oxazolines valinol is derived from the amino acid valine Sphingosine is a component of some cell membrane. 1-Aminoalcohols are better...

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Amino acid

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opposite is the case with cysteine, phenylalanine, tryptophan, methionine, valine, leucine, isoleucine, which are highly reactive, or complex, or hydrophobic...

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Valinol

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organic compound named after, and commonly produced from, the amino acid valine. The compound is chiral and is produced almost exclusively as the S‑isomer...

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GTG

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car racing team GTG, a codon in the DNA codon table for the amino acid valine G2G, government to government, in e-governance This disambiguation page...

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Fatal insomnia

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129 of the mutant allele, whereas fCJD is linked to the presence of the valine codon at that position. The disease occurs when there is a change of amino...

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Isopenicillin N synthase

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from δ-(L-α-aminoadipoyl)-L-cysteinyl-D-valine (LLD-ACV). N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2 ⇌ {\displaystyle \rightleftharpoons...

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Isoleucine

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synthase) Acetohydroxy acid isomeroreductase Dihydroxyacid dehydratase Valine aminotransferase Isoleucine is both a glucogenic and a ketogenic amino acid...

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Tripeptide

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A tripeptide (example Val-Gly-Ala) with green marked amino end (L-Valine) and blue marked carboxyl end (L-Alanine)...

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Oligopeptide

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A tripeptide (example Val-Gly-Ala) with green marked amino end (L-Valine) and blue marked carboxyl end (L-Alanine)...

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Protein digestibility corrected amino acid score

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Isoleucine 25 Leucine 55 Lysine 51 Methionine + Cysteine (SAA) 25 Phenylalanine + Tyrosine (AAA) 47 Threonine 27 Tryptophan 7 Valine 32 Histidine 18 Total 287...

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Maize

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Methionine 0.067 g Cystine 0.026 g Phenylalanine 0.150 g Tyrosine 0.123 g Valine 0.185 g Arginine 0.131 g Histidine 0.089 g Alanine 0.295 g Aspartic acid...

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