NADPH oxidase (nicotinamide adenine dinucleotide phosphate oxidase) is a membrane-bound enzyme complex that faces the extracellular space. It can be found in the plasma membrane as well as in the membranes of phagosomes used by neutrophil white blood cells to engulf microorganisms. Human isoforms of the catalytic component of the complex include NOX1, NOX2, NOX3, NOX4, NOX5, DUOX1, and DUOX2.[1]
NADPHoxidase (nicotinamide adenine dinucleotide phosphate oxidase) is a membrane-bound enzyme complex that faces the extracellular space. It can be found...
(most importantly the superoxide radical due to defective phagocyte NADPHoxidase) used to kill certain ingested pathogens. This leads to the formation...
NADPHoxidase 4 is an enzyme that in humans is encoded by the NOX4 gene, and is a member of the NOX family of NADPHoxidases. Oxygen sensing is essential...
encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPHoxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide...
acid chain elongation. The NADPH system is also responsible for generating free radicals in immune cells by NADPHoxidase. These radicals are used to...
NADPHoxidase 2 (Nox2), also known as cytochrome b(558) subunit beta or Cytochrome b-245 heavy chain, is a protein that in humans is encoded by the NOX2...
types via NADPHoxidase (NOX) or dual oxidase (DUOX). This new family of proteins, termed the NOX/DUOX family or NOX family of NADPHoxidases, consists...
discoveries have been the NADPHoxidase and causes of Chronic Granulomatous Disease (CGD): The identity of the NADPHoxidase that generates superoxide...
hot water, alcohol, benzene, chloroform, and ether.[citation needed] NADPHoxidase is an enzyme that effectively reduces O2 to superoxide (O2–•), which...
NADPHoxidase 1 is an enzyme that in humans is encoded by the NOX1 gene. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH...
NADPHoxidase, EF-hand calcium binding domain 5, also known as NOX5, is a protein which in humans is encoded by the NOX5 gene. NOX5 is a novel NADPH oxidase...
enzyme NADPHoxidase for use in oxygen-dependent killing mechanisms of invading pathogens. Mutations in the gene coding for the NADPHoxidase cause an...
Neutrophils and other phagocytes use peroxide to kill bacteria. The enzyme NADPHoxidase generates superoxide within the phagosome, which is converted via hydrogen...
Nox (platform), a piece of the software-defined networking ecosystem NADPHoxidase, a membrane-bound enzyme complex Nox (Stargate), a race in the television...
respiratory burst is known as nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, which is composed of five subunits. One component is a membrane cytochrome...
types via NADPHoxidase (NOX) or dual oxidase (DUOX). This new family of proteins, termed the NOX/DUOX family or NOX family of NADPHoxidases, consists...
NADPHoxidase activator 1 is an enzyme that in humans is encoded by the NOXA1 gene. GRCh38: Ensembl release 89: ENSG00000188747 – Ensembl, May 2017 GRCm38:...
oxygen-derived compounds, including superoxide (which is produced by NADPHoxidase). Superoxide decays to oxygen and hydrogen peroxide, which is used in...
NADPHoxidase 3 is an enzyme that in humans is encoded by the NOX3 gene. NADPHoxidases, such as NOX3, are plasma membrane-associated enzymes found in...
production. The respiratory burst involves the activation of the enzyme NADPHoxidase, which produces large quantities of superoxide, a reactive oxygen species...
picture of the pathway is emerging. The process is thought to begin with NADPHoxidase activation of protein-arginine deiminase 4 (PAD4) via reactive oxygen...
cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein...
by phagocytes, known as the NADPHoxidase. With Yael Bromberg, he described a novel method of activating the NADPHoxidase derived from resting phagocytes...
alkylated base damage. Phosphorylation of the cytosolic components of NADPHoxidase, a large membrane-bound, multi-protein enzyme present in phagocytic...
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