NOXA1 information

NOXA1
Identifiers
Aliases	NOXA1, NY-CO-31, SDCCAG31, p51NOX, NADPH oxidase activator 1
External IDs	OMIM: 611255; MGI: 2449980; HomoloGene: 18156; GeneCards: NOXA1; OMA:NOXA1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	137,434,406 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	24,985,161 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; mucosa of transverse colon; ; right uterine tube; ; right frontal lobe; ; anterior pituitary; ; Brodmann area 9; ; nucleus accumbens; ; body of pancreas; ; right hemisphere of cerebellum; ; cingulate gyrus;
	Top expressed in
	ileum; ; colon; ; duodenum; ; jejunum; ; stomach; ; embryo; ; embryo; ; uterus; ; lung; ; liver;
	More reference expression data
	n/a
Gene ontology
Molecular function	SH3 domain binding; enzyme binding; superoxide-generating NADPH oxidase activator activity; protein binding;
Cellular component	cytoplasm; cytosol; plasma membrane; membrane; NADPH oxidase complex;
Biological process	regulation of respiratory burst; superoxide metabolic process; regulation of hydrogen peroxide metabolic process; positive regulation of catalytic activity; superoxide anion generation;
	Sources:Amigo / QuickGO
Orthologs
	10811
	241275
	ENSG00000188747
	ENSMUSG00000036805
	Q86UR1
	Q8CJ00
	NM_001256067; NM_001256068; NM_006647
	NM_001163626; NM_172204
	NP_001242996; NP_001242997; NP_006638
	NP_001157098; NP_757341
	Wikidata
View/Edit Human	View/Edit Mouse

NADPH oxidase activator 1 is an enzyme that in humans is encoded by the NOXA1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000188747 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036805 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Scanlan MJ, Chen YT, Williamson B, Gure AO, Stockert E, Gordan JD, Türeci O, Sahin U, Pfreundschuh M, Old LJ (May 1998). "Characterization of human colon cancer antigens recognized by autologous antibodies". International Journal of Cancer. 76 (5): 652–8. doi:10.1002/(SICI)1097-0215(19980529)76:5<652::AID-IJC7>3.0.CO;2-P. PMID 9610721.
^ "Entrez Gene: NOXA1 NADPH oxidase activator 1".

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