Dual oxidase 2, also known as DUOX2 or ThOX2 (for thyroid oxidase), is an enzyme that in humans is encoded by the DUOX2 gene.[5][6] Dual oxidase is an enzyme that was first identified in the mammalian thyroid gland. In humans, two isoforms are found; hDUOX1 and hDUOX2 (this enzyme). The protein location is not exclusive to thyroid tissue; hDUOX1 is prominent in airway epithelial cells[7] and hDUOX2 in the salivary glands and gastrointestinal tract.[8][9][10]
^ abcGRCh38: Ensembl release 89: ENSG00000140279 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000068452 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Dupuy C, Ohayon R, Valent A, Noël-Hudson MS, Dème D, Virion A (December 1999). "Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas". J. Biol. Chem. 274 (52): 37265–9. doi:10.1074/jbc.274.52.37265. PMID 10601291.
^De Deken X, Wang D, Many MC, Costagliola S, Libert F, Vassart G, Dumont JE, Miot F (July 2000). of Two Human Thyroid cDNAs Encoding New Members of the NADPH Oxidase Family.pdf "Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family" (PDF). J. Biol. Chem. 275 (30): 23227–33. doi:10.1074/jbc.M000916200. PMID 10806195. S2CID 19424568. {{cite journal}}: Check |url= value (help)
^Harper RW, Xu C, Eiserich JP, Chen Y, Kao CY, Thai P, Setiadi H, Wu R (August 2005). "Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium". FEBS Lett. 579 (21): 4911–7. doi:10.1016/j.febslet.2005.08.002. PMID 16111680. S2CID 34266530.
Dualoxidase2, also known as DUOX2 or ThOX2 (for thyroid oxidase), is an enzyme that in humans is encoded by the DUOX2 gene. Dualoxidase is an enzyme...
Dualoxidase 1, also known as DUOX1 or ThOX1 (for thyroid oxidase), is an enzyme which in humans is encoded by the DUOX1 gene. DUOX1 was first identified...
NADPH oxidase (nicotinamide adenine dinucleotide phosphate oxidase) is a membrane-bound enzyme complex that faces the extracellular space. It can be found...
NADPH oxidase enzyme complex. Other cells in the respiratory tract also produce superoxide and hydrogen peroxide through the activity of dualoxidase2 proteins...
of lactoperoxidase on thiocyanate and hydrogen peroxide produced by dualoxidase2 proteins, also known as Duox2. Thiocyanate secretion in cystic fibrosis...
Monoamine oxidase B, also known as MAO-B, is an enzyme that in humans is encoded by the MAOB gene. The protein encoded by this gene belongs to the flavin...
may occur with stopping. It is not recommended together with a monoamine oxidase inhibitor, although evidence supporting the danger of this combination...
in patients experiencing depression who are using SSRIs and Monoamine Oxidase Inhibitors (MAOIs). Currently, SSRIs are the preferred treatment for depression...
extensive crosslinking by members of the lysyl oxidase and lysyl oxidase like family of copper-dependent amine oxidases into amorphous elastin, a highly resilient...
(proposed brand name Consonar) is a reversible inhibitor of monoamine oxidase A (RIMA) discovered by Ciba-Geigy. The compound was primarily researched...
elimination of hydrogen peroxide primarily through the dual function of the same egg oxidase, and secondarily through cytoplasmic ROS scavengers, such...
inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a Reversible inhibitor of monoamine oxidase A (RIMA). Harmine does...
much more metabolically stable and resistant to degradation by monoamine oxidase, resulting in increased potency and greatly lengthened half-life. This...
original on 2 December 2013. Retrieved 23 November 2013. Shulman KI, Herrmann N, Walker SE (October 2013). "Current place of monoamine oxidase inhibitors...
Xanthine oxidase inhibitors, including allopurinol, febuxostat and topiroxostat, decrease the production of uric acid, by interfering with xanthine oxidase.[citation...
neurotransmitters affect survival outcomes, controlled by the enzyme monoamine oxidase; Helicopter Underwater Escape Training at Survival Systems in Dartmouth...
H2SO4) forms a blue peroxide CrO(O2)2. The aerobic oxidation of glucose in the presence of the enzyme glucose oxidase produces hydrogen peroxide. The conversion...
promise in its correlation with ASPD is the gene that encodes for Monoamine oxidase A (MAO-A), an enzyme that breaks down monoamine neurotransmitters such...
Werck-Reichhart, D (November 2013). "Geraniol hydroxylase and hydroxygeraniol oxidase activities of the CYP76 family of cytochrome P450 enzymes and potential...
accounted for by macroglobulins. Ceruloplasmin exhibits a copper-dependent oxidase activity, which is associated with possible oxidation of Fe2+ (ferrous...
cirrhosis) Being under six years of age Patients who are taking monoamine oxidase inhibitors (MAOIs) or have taken them within the last 14 days Amitriptyline...
for the cytochrome c oxidase family. Thus, the two isozymes found in humans, PTGS1 and PTGS2, are frequently called COX-1 and COX-2 in medical literature...
withdrawal. It should be avoided in individuals who are taking monoamine oxidase inhibitors (MAOIs). The label recommends that caution should be exercised...
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