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Methyl group information


Different ways of representing a methyl group (highlighted in blue)

In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula CH3 (whereas normal methane has the formula CH4). In formulas, the group is often abbreviated as Me. This hydrocarbon group occurs in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, bounded to the rest of the molecule by a single covalent bond (−CH3), it can be found on its own in any of three forms: methanide anion (CH3), methylium cation (CH+3) or methyl radical (CH
3
). The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed.[1]

  1. ^ March, Jerry (1992). Advanced organic chemistry: reactions, mechanisms, and structure. John Wiley & Sons. ISBN 0-471-60180-2.

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Methyl group

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In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula...

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Alkyl group

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(unspecified) alkyl group. The smallest alkyl group is methyl, with the formula −CH3. Alkylation is the addition of alkyl groups to molecules, often by...

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Methanol

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aliphatic alcohol, with the chemical formula CH3OH (a methyl group linked to a hydroxyl group, often abbreviated as MeOH). It is a light, volatile, colorless...

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Methylcobalamin

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It differs from cyanocobalamin in that the cyano group at the cobalt is replaced with a methyl group. Methylcobalamin features an octahedral cobalt(III)...

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Methoxy group

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organic chemistry, a methoxy group is the functional group consisting of a methyl group bound to oxygen. This alkoxy group has the formula R−O−CH3. On...

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Toluene

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mono-substituted benzene derivative, consisting of a methyl group (CH3) attached to a phenyl group by a single bond. As such, its systematic IUPAC name...

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Methyl ether

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Methyl ether may refer to: Any chemical compound of the ether class that includes a methyl group Dimethyl ether, often simply called methyl ether Methoxy...

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Methyltransferase

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sulfur serves as the leaving group and the methyl group attached to it acts as the electrophile that transfers the methyl group to the enzyme substrate. SAM...

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Methylamine

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derivative of ammonia, but with one hydrogen atom being replaced by a methyl group. It is the simplest primary amine. Methylamine is sold as a solution...

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Methylation

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a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group. Methylation is a form of alkylation, with a methyl group replacing...

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Polypropylene

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polyethylene, especially in solution behavior and electrical properties. The methyl group improves mechanical properties and thermal resistance, although the chemical...

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Methyl violet

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Methyl violet is a family of organic compounds that are mainly used as dyes. Depending on the number of attached methyl groups, the color of the dye can...

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Acetyl group

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called ethanoyl. The acetyl group contains a methyl group (−CH3) single-bonded to a carbonyl (C=O), making it an acyl group. The carbonyl center of an...

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Vitamin E

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methyl group (CH3) attached. For beta(β)-tocopherol: R1 = methyl group, R2 = H, R3 = methyl group. For gamma(γ)-tocopherol: R1 = H, R2 = methyl group...

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TNT

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more specifically 2,4,6-trinitrotoluene, and by its preferred IUPAC name 2-methyl-1,3,5-trinitrobenzene,[citation needed] is a chemical compound with the...

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Anisole

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synthetic compounds. Structurally, it is an ether (−O−) with a methyl (−CH3) and phenyl (−C6H5) group attached. Anisole is a standard reagent of both practical...

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Demethylation

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resulting in the removal of a methyl group (CH3) from a molecule. A common way of demethylation is the replacement of a methyl group by a hydrogen atom, resulting...

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Vitamin B12

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dimethylbenzimidazole group. The sixth coordination site, the reactive center, is variable, being a cyano group (–CN), a hydroxyl group (–OH), a methyl group (–CH3)...

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Trifluoromethyl group

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The trifluoromethyl group is a functional group that has the formula -CF3. The naming of is group is derived from the methyl group (which has the formula...

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Amphetamine

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positional isomer of amphetamine that differs only in the placement of the methyl group. Amphetamine is used to treat attention deficit hyperactivity disorder...

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Dichloromethyl methyl ether

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Dichloromethyl methyl ether (HCl2COCH3) is an organic compound that belongs to the class of ethers with a dichloromethyl group and a methyl group. It can be...

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DNA methylation

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DNA methylation is a biological process by which methyl groups are added to the DNA molecule. Methylation can change the activity of a DNA segment without...

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Electrophilic aromatic directing groups

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nitration. The methyl group in toluene is small and will lead the ortho product being the major product. On the other hand, the t-butyl group is very bulky...

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Methyl anthranilate

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Methyl anthranilate, also known as MA, methyl 2-aminobenzoate, or carbomethoxyaniline, is an ester of anthranilic acid. Its chemical formula is C8H9NO2...

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Aryl group

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Note that a phenyl group is not the same as a benzyl group, the latter consisting of a phenyl group attached to a methyl group and a molecular formula...

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Methylene group

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deprotonated to form a methylene group. Methylidene group Carbene Methylene (compound) Methyl group Methine "methylene (preferred IUPAC name" (PDF). "methylidene...

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Trimethylsilyl group

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A trimethylsilyl group (abbreviated TMS) is a functional group in organic chemistry. This group consists of three methyl groups bonded to a silicon atom...

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Cresol

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source, creosote. In its chemical structure, a molecule of cresol has a methyl group substituted onto the ring of phenol. There are three forms (isomers)...

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Organyl group

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Acetonyl group Acyl group (e.g. acetyl group, benzoyl group) Alkyl group (e.g., methyl group, ethyl group) Alkenyl group (e.g., vinyl group, allyl group) Alkynyl...

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