Trifluoromethyl group covalently bonded to an R group
The trifluoromethyl group is a functional group that has the formula -CF3. The naming of is group is derived from the methyl group (which has the formula -CH3), by replacing each hydrogen atom by a fluorine atom. Some common examples are trifluoromethane H–CF 3, 1,1,1-trifluoroethane H 3C–CF 3, and hexafluoroacetone F 3C–CO–CF 3. Compounds with this group are a subclass of the organofluorines.
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The trifluoromethylgroup is a functional group that has the formula -CF3. The naming of is group is derived from the methyl group (which has the formula...
organic chemistry describes any organic reaction that introduces a trifluoromethylgroup in an organic compound. Trifluoromethylated compounds are of some...
formed. An electron donating group (EDG) or electron releasing group (ERG, Z in structural formulas) is an atom or functional group that donates some of its...
diazonium salts are a group of organic compounds sharing a common functional group [R−N+≡N]X− where R can be any organic group, such as an alkyl or an...
fluorine atoms and consequent electron-withdrawing nature of the trifluoromethylgroup weakens the oxygen-hydrogen bond (allowing for greater acidity)...
additional stabilization is achieved by the trifluoromethylgroup, which acts as a strong electron-withdrawing group using the sulfur atom as a bridge. Triflates...
principle, the trichloromethyl group generally lowers the basicity of organic compounds, e.g. trichloroethanol. Trifluoromethylgroup Trichloromethoxy "Trichloromethyl...
(same structure as clenbuterol but one of the chloro groups has been changed to a trifluoromethylgroup instead). Cimaterol Center for Veterinary Medicine...
drugs and agrochemicals contain only one fluorine center or one trifluoromethylgroup. Unlike other greenhouse gases in the Paris Agreement, hydrofluorocarbons...
esters are named. For example, if the R2 group is a methyl group and the R1 group is a trifluoromethylgroup, the resulting compound is methyl trifluoromethanesulfonate...
replaces some fluorine atoms with trifluoromethylgroups, perfluoroalkoxy alkanes do the same with trifluoromethoxy groups, and Nafion contains perfluoroether...
drugs and agrochemicals contain only one fluorine center or one trifluoromethylgroup. Unlike other greenhouse gases in the Paris Agreement, hydrofluorocarbons...
organohalides. Notably, many pharmaceuticals such as Prozac have trifluoromethylgroups. For information on inorganic halide chemistry, see halide. Halocarbons...
TFNM) is a toxic organic compound consisting of a trifluoromethylgroup covalently bound to a nitroso group. Its distinctive deep blue color is unusual for...
system has low steric hindrance to maximize potency, while the 3-trifluoromethylgroup provides superior selectivity and potency. To explain the selectivity...
a reagent used in organic chemistry for the introduction of the trifluoromethylgroup. The compound was first prepared in 1984 by Ingo Ruppert and further...
species bis(trifluoromethyl)acetolactone ((CF 3) 2C 2O 2), which has increased electronic stabilisation due to its two trifluoromethylgroups, is known...
this compound was found to be a suitable reagent for introducing trifluoromethylgroups onto electron-rich aromatic compounds by Langlois; this reagent...
an analogue of bisphenol A in which the two methyl groups are replaced with trifluoromethylgroups. It exists as a white to light-gray powder. Bisphenol...
constant is about 10+6, due to the electron withdrawing effect of the trifluoromethylgroups. Similarly, the conversion of chloral (Cl 3C)HC=O to chloral hydrate...
timoprazole was the benzimidazole part of its structure. Addition of a trifluoromethylgroup to the benzimidazole moiety led to a series of very active compounds...
functional group is a substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions. The same functional group will undergo...
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