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Intrinsic pathway information


In molecular biology, the term intrinsic pathway may refer to multiple cascades of protein interactions:

  • The intrinsic pathway of apoptosis (also known as the mitochondrial pathway, intracellular pathway, or intrinsic apoptosis), cell death initiated by changes in mitochondria.
  • The intrinsic pathway of blood coagulation (also known as the contact activation pathway), a cascade of enzymatic reactions resulting in blood clotting.

and 28 Related for: Intrinsic pathway information

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Intrinsic pathway

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intrinsic pathway may refer to multiple cascades of protein interactions: The intrinsic pathway of apoptosis (also known as the mitochondrial pathway...

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Apoptosis

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activation mechanisms are the intrinsic pathway (also called the mitochondrial pathway) and the extrinsic pathway. The intrinsic pathway is activated by intracellular...

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Coagulation

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has two initial pathways which lead to fibrin formation. These are the contact activation pathway (also known as the intrinsic pathway), and the tissue...

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Programmed cell death

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potential pathways that may be followed when apoptosis is needed. There is the extrinsic pathway and the intrinsic pathway. Both pathways involve the...

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Prothrombin time

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activated partial thromboplastin time (aPTT) which measures the intrinsic pathway and common pathway of coagulation.[citation needed] The reference range for...

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Partial thromboplastin time

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consecutive series of biochemical reactions known as the intrinsic pathway and common pathway of coagulation. The PTT indirectly measures action of the...

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Kidney ischemia

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two: extrinsic and intrinsic pathways. The extrinsic pathway are directly induced upon renal ischemic injury, while intrinsic pathways are dependent on...

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Haemophilia

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factor V. Haemophilia A, B, and C prevent the intrinsic pathway from functioning properly; this clotting pathway is necessary when there is damage to the endothelium...

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Inhibitor of apoptosis

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Inhibitors of apoptosis are a group of proteins that mainly act on the intrinsic pathway that block programmed cell death, which can frequently lead to cancer...

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Thromboplastin

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partial thromboplastin. Partial thromboplastin was used to measure the intrinsic pathway. This test is called the aPTT, or activated partial thromboplastin...

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Factor X

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in a complex known as intrinsic pathway; and factor VII with its cofactor, tissue factor in a complex known as extrinsic pathway. It is therefore the first...

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Visual pathway lesions

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The visual pathway consists of structures that carry visual information from the retina to the brain. Lesions in that pathway cause a variety of visual...

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Factor XII

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charged surfaces, such as glass. This is the starting point of the intrinsic pathway. Factor XII can also be used to start coagulation cascades in laboratory...

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Reactive oxygen species

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can induce apoptosis through both the extrinsic and intrinsic pathways. In the extrinsic pathway of apoptosis, ROS are generated by Fas ligand as an upstream...

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Vitamin K deficiency

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activity in factors of both the intrinsic pathway (F-IX) which is monitored by PTT, as well as the extrinsic pathway (F-VII) which is monitored by PT...

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Tissue factor

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tissue factor forms the extrinsic pathway of coagulation. This is opposed to the intrinsic (amplification) pathway, which involves both activated factor...

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Phospholipid scramblase

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mitochondria during apoptosis may be a key regulator initiating the intrinsic apoptotic pathways. Phospholipid scramblase 1 (PLSCR1), a lipid-binding protein...

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Mitochondrial outer membrane permeabilization

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death) can be activated. It is part of the intrinsic pathway of apoptosis, also known as the mitochondrial pathway. MOMP is known as the point of no return...

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Von Willebrand factor

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extracellular matrix Biological process hemostasis blood coagulation, intrinsic pathway platelet degranulation extracellular matrix organization blood coagulation...

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Kininogen

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regions. During the contact activation system (CAS), also known as the intrinsic pathway, the binding of HK, factor XII (FXII), and prekallikrein (PK) to an...

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Dopaminergic pathways

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pathway, the mesocortical pathway, the nigrostriatal pathway, and the tuberoinfundibular pathway. The mesolimbic pathway and the mesocortical pathway...

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Wnt signaling pathway

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The Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors...

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Sleep deprivation

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which itself activates the intrinsic pathway of apoptosis and prevents autophagy, which also induces the mitochondrial pathway of apoptosis. Sleep outside...

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Antithrombin

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of antithrombin are those of the contact activation pathway (formerly known as the intrinsic pathway), namely the activated forms of Factor X (Xa), Factor...

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Mitochondrion

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in the mitochondria passes a certain threshold, it stimulates the intrinsic pathway of apoptosis in part by collapsing the mitochondrial membrane potential...

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Caspase

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for apoptosis. Examples of caspase cascade during apoptosis: Intrinsic apoptopic pathway: During times of cellular stress, mitochondrial cytochrome c...

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Norepinephrine

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Noradrenaline Acting on Alpha1 Adrenoceptor and by Triggering Mitochondrial Intrinsic Pathway". Frontiers in Neurology. 7: 25. doi:10.3389/fneur.2016.00025. PMC 4779900...

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Contact activation system

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This test is used to measure the contact activation pathway (intrinsic pathway) and the common pathway of clotting. FXII is a zymogen, which means that it...

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