In molecular biology, the term intrinsic pathway may refer to multiple cascades of protein interactions:
The intrinsic pathway of apoptosis (also known as the mitochondrial pathway, intracellular pathway, or intrinsic apoptosis), cell death initiated by changes in mitochondria.
The intrinsic pathway of blood coagulation (also known as the contact activation pathway), a cascade of enzymatic reactions resulting in blood clotting.
Topics referred to by the same term
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activation mechanisms are the intrinsicpathway (also called the mitochondrial pathway) and the extrinsic pathway. The intrinsicpathway is activated by intracellular...
has two initial pathways which lead to fibrin formation. These are the contact activation pathway (also known as the intrinsicpathway), and the tissue...
potential pathways that may be followed when apoptosis is needed. There is the extrinsic pathway and the intrinsicpathway. Both pathways involve the...
activated partial thromboplastin time (aPTT) which measures the intrinsicpathway and common pathway of coagulation.[citation needed] The reference range for...
consecutive series of biochemical reactions known as the intrinsicpathway and common pathway of coagulation. The PTT indirectly measures action of the...
two: extrinsic and intrinsicpathways. The extrinsic pathway are directly induced upon renal ischemic injury, while intrinsicpathways are dependent on...
factor V. Haemophilia A, B, and C prevent the intrinsicpathway from functioning properly; this clotting pathway is necessary when there is damage to the endothelium...
Inhibitors of apoptosis are a group of proteins that mainly act on the intrinsicpathway that block programmed cell death, which can frequently lead to cancer...
partial thromboplastin. Partial thromboplastin was used to measure the intrinsicpathway. This test is called the aPTT, or activated partial thromboplastin...
in a complex known as intrinsicpathway; and factor VII with its cofactor, tissue factor in a complex known as extrinsic pathway. It is therefore the first...
The visual pathway consists of structures that carry visual information from the retina to the brain. Lesions in that pathway cause a variety of visual...
charged surfaces, such as glass. This is the starting point of the intrinsicpathway. Factor XII can also be used to start coagulation cascades in laboratory...
can induce apoptosis through both the extrinsic and intrinsicpathways. In the extrinsic pathway of apoptosis, ROS are generated by Fas ligand as an upstream...
activity in factors of both the intrinsicpathway (F-IX) which is monitored by PTT, as well as the extrinsic pathway (F-VII) which is monitored by PT...
tissue factor forms the extrinsic pathway of coagulation. This is opposed to the intrinsic (amplification) pathway, which involves both activated factor...
mitochondria during apoptosis may be a key regulator initiating the intrinsic apoptotic pathways. Phospholipid scramblase 1 (PLSCR1), a lipid-binding protein...
death) can be activated. It is part of the intrinsicpathway of apoptosis, also known as the mitochondrial pathway. MOMP is known as the point of no return...
regions. During the contact activation system (CAS), also known as the intrinsicpathway, the binding of HK, factor XII (FXII), and prekallikrein (PK) to an...
pathway, the mesocortical pathway, the nigrostriatal pathway, and the tuberoinfundibular pathway. The mesolimbic pathway and the mesocortical pathway...
The Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors...
which itself activates the intrinsicpathway of apoptosis and prevents autophagy, which also induces the mitochondrial pathway of apoptosis. Sleep outside...
of antithrombin are those of the contact activation pathway (formerly known as the intrinsicpathway), namely the activated forms of Factor X (Xa), Factor...
in the mitochondria passes a certain threshold, it stimulates the intrinsicpathway of apoptosis in part by collapsing the mitochondrial membrane potential...
for apoptosis. Examples of caspase cascade during apoptosis: Intrinsic apoptopic pathway: During times of cellular stress, mitochondrial cytochrome c...
Noradrenaline Acting on Alpha1 Adrenoceptor and by Triggering Mitochondrial IntrinsicPathway". Frontiers in Neurology. 7: 25. doi:10.3389/fneur.2016.00025. PMC 4779900...
This test is used to measure the contact activation pathway (intrinsicpathway) and the common pathway of clotting. FXII is a zymogen, which means that it...