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Heme transporter information


A heme transporter is a protein that delivers heme to the various parts of a biological cell that require it.

Heme is a major source of dietary iron in humans and other mammals, and its synthesis in the body is well understood, but heme pathways are not as well understood. It is likely that heme is tightly regulated for two reasons: the toxic nature of iron in cells, and the lack of a regulated excretory system for excess iron. Understanding heme pathways is therefore important in understanding diseases such as hemochromatosis and anemia.

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Heme transporter

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A heme transporter is a protein that delivers heme to the various parts of a biological cell that require it. Heme is a major source of dietary iron in...

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Glucose transporter

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Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane, a process known as facilitated...

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Haem carrier protein 1

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the SLC46A1 folate transporter. HCP1 is a protein found in the small intestine that plays a role in the absorption of dietary heme, a form of iron that...

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Solute carrier family

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Folate transporter (SLC46A1, SLC46A2, SLC46A3) multidrug and toxin extrusion (SLC47A1, SLC47A2) Heme transporter family (SLC48A1) Heme transporter (FLVCR1(SLC49A1)...

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Serotonin transporter

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The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that...

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Membrane transport protein

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A membrane transport protein (or simply transporter) is a membrane protein involved in the movement of ions, small molecules, and macromolecules, such...

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Vesicular monoamine transporter 2

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carrier family 18 member 2 (SLC18A2) also known as vesicular monoamine transporter 2 (VMAT2) is a protein that in humans is encoded by the SLC18A2 gene...

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GLUT4

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Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by...

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GLUT2

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Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein...

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Hemoglobin

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(about 20–25% of the total) as carbaminohemoglobin, in which CO2 binds to the heme protein. The molecule also carries the important regulatory molecule nitric...

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Iron preparation

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transportation of non-heme iron across the apical membrane is through divalent metal transporter 1(DMT1) while that of heme iron is through heme carrier protein...

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Zinc transporter protein

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Zinc transporter proteins (Zrt), or simply zinc transporters, are membrane transport proteins of the solute carrier family which control the membrane...

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Ion transporter

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In biology, a transporter is a transmembrane protein that moves ions (or other small molecules) across a biological membrane to accomplish many different...

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ABC transporter

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The ABC transporters, ATP synthase (ATP)-binding cassette transporters are a transport system superfamily that is one of the largest and possibly one of...

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Monocarboxylate transporter 1

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Monocarboxylate transporter 1 is a ubiquitous protein that in humans is encoded by the SLC16A1 gene (also known as MCT1). It is a proton coupled monocarboxylate...

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Glutamate transporter

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Glutamate transporters are a family of neurotransmitter transporter proteins that move glutamate – the principal excitatory neurotransmitter – across...

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Human iron metabolism

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S2CID 44351106. Rouault, Tracey A. (2005-09-09). "The Intestinal Heme Transporter Revealed". Cell. 122 (5): 649–651. doi:10.1016/j.cell.2005.08.027....

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Cytochrome c family

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electron transfer to the heme group, apo-cytochrome handling and attachment of the heme to the apo-cytochrome. An ABC-transporter-like complex formed by...

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Urea transporter

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A urea transporter is a membrane transport protein, transporting urea. Humans and other mammals have two types of urea transport proteins, UT-A and UT-B...

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Norepinephrine transporter

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The norepinephrine transporter (NET), also known as noradrenaline transporter (NAT), is a protein that in humans is encoded by the solute carrier family...

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GLUT1

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Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that...

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Dopamine transporter

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The dopamine transporter (DAT, also sodium-dependent dopamine transporter) is a membrane-spanning protein coded for in the human by the SLC6A3 gene (also...

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Peptide transporter 1

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Peptide transporter 1 (PepT 1) also known as solute carrier family 15 member 1 (SLC15A1) is a protein that in humans is encoded by SLC15A1 gene. PepT...

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Iron in biology

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S2CID 44351106. Rouault, Tracey A. (2005-09-09). "The Intestinal Heme Transporter Revealed". Cell. 122 (5): 649–651. doi:10.1016/j.cell.2005.08.027....

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