The HIV-1 Rev response element (RRE) is a highly structured, ~350 nucleotide RNA segment present in the Env coding region of unspliced and partially spliced viral mRNAs. In the presence of the HIV-1 accessory protein Rev, HIV-1 mRNAs that contain the RRE can be exported from the nucleus to the cytoplasm for downstream events such as translation and virion packaging.[1][2]
^Cullen, Bryan R (2003). "Nuclear mRNA export: Insights from virology". Trends in Biochemical Sciences. 28 (8): 419–424. doi:10.1016/S0968-0004(03)00142-7. PMID 12932730.
^Pollard, Victoria W.; Malim, Michael H. (1998). "The Hiv-1 Rev Protein". Annual Review of Microbiology. 52: 491–532. doi:10.1146/annurev.micro.52.1.491. PMID 9891806.
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The HIV-1 Revresponseelement (RRE) is a highly structured, ~350 nucleotide RNA segment present in the Env coding region of unspliced and partially spliced...
in the intron separating coding exon of Tat and Rev, known as the HIVRevresponseelement (RRE). Rev is important for the synthesis of major viral proteins...
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the HIV-1 ribosomal frameshift signal will be vital to understanding the reason for high affinity and the method of action. HIVRevresponseelement Retrovirus...
two regulatory genes, tat and rev. They may also have additional accessory genes depending on the virus (e.g., for HIV-1: vif, vpr, vpu, nef) whose products...
the germ cell development in mice CREM gene were disrupted. The cAMP responseelement sites can be found in the promoter region of some postmeiotic genes...
Balzarini J (2007). "The regulation of HIV-1 transcription: molecular targets for chemotherapeutic intervention". Med Res Rev. 26 (5): 595–625. doi:10.1002/med...
transcription factors that produce these alterations are ΔFosB, cAMP responseelement binding protein (CREB), and nuclear factor kappa B (NFκB). ΔFosB plays...
export protein, Rem, with resemblance to the human immunodeficiency virus (HIV) Rev protein, and is therefore the first complex murine retrovirus to be documented...
initiation factor 5A with the human immunodeficiency virus type 1 Revresponseelement RNA and U6 snRNA requires deoxyhypusine or hypusine modification"...
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Percipalle P (December 1997). "Interactions between HIVRev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding...
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have included population control, negative eugenics, limiting the spread of HIV or other venereal diseases and the desire to commit genocide against ethnic...
Rev. Immunol. 14: 649–83. doi:10.1146/annurev.immunol.14.1.649. PMID 8717528. Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1...
S2CID 13377783. Copeland KF (2005). "Modulation of HIV-1 transcription by cytokines and chemokines". Mini Rev Med Chem. 5 (12): 1093–101. doi:10.2174/138955705774933383...
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caused by viruses in Riboviria, which includes coronaviruses, ebola virus, HIV, influenza viruses, and the rabies virus. These viruses and others have been...