The Fibronectin type III domain is an evolutionarily conserved protein domain that is widely found in animal proteins. The fibronectin protein in which this domain was first identified contains 16 copies of this domain. The domain is about 100 amino acids long and possesses a beta sandwich structure. Of the three fibronectin-type domains, type III is the only one without disulfide bonding present. Fibronectin domains are found in a wide variety of extracellular proteins. They are widely distributed in animal species, but also found sporadically in yeast, plant and bacterial proteins.
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The FibronectintypeIIIdomain is an evolutionarily conserved protein domain that is widely found in animal proteins. The fibronectin protein in which...
Fibronectintype II domain is a collagen-binding protein domain. Fibronectin is a multi-domain glycoprotein, found in a soluble form in plasma, and in...
Pikachurin, also known as AGRINL (AGRINL) and EGF-like, fibronectintype-III and laminin G-like domain-containing protein (EGFLAM), is a protein that in humans...
FibronectintypeIIIdomain-containing protein 5, the precursor of irisin, is a type I transmembrane glycoprotein that is encoded by the FNDC5 gene. Irisin...
signal transduction. The common cytokine-binding domain is related to the FibronectintypeIIIdomain. The signal transducing chains are often shared between...
Monobodies are synthetic binding proteins constructed using a fibronectintypeIIIdomain (FN3) as a molecular scaffold. Specifically, this class of binding...
in the number and identity of fibronectintypeIIIdomain repeats. Tenascin-C has been shown to interact with fibronectin. This interaction is shown to...
Fibronectintype-IIIdomain-containing protein 3a is a protein that in humans is encoded by the FNDC3A gene. GRCh38: Ensembl release 89: ENSG00000102531...
14 EGF-like repeats towards the N-terminal end, and 8 or more fibronectin-IIIdomains which vary upon species and variant. Tenascin-C is the most intensely...
Tenascin assembly domain (TAD), a series of 18.5 repeats of epidermal growth factor (EGF)-like motif, a high number of FibronectintypeIII (FNIII) module...
(2007). "Monobodies: antibody mimics based on the scaffold of the fibronectintypeIIIdomain". Protein Engineering Protocols. Methods Mol. Biol. Vol. 352...
discovered in 2002 by two independent groups of researchers. Irisin (fibronectintypeIIIdomain-containing protein 5 or FNDC5), a recently described myokine...
characterized by their extracellular domains containing Ig-like domains. The Ig domains are then followed by FibronectintypeIIIdomain repeats and IgSFs are anchored...
conserved. The receptors have two typeIIIfibronectindomains in their extracellular domain. The interface of these two domains forms the cytokine binding site...
of two types of modules, also referred to as protein domains (244 copies in total): type I fibronectintypeIIIdomain (132 copies) and type II immunoglobulin...
form independent networks and are associated with type IV collagen networks via entactin, fibronectin, and perlecan. The proteins also bind to cell membranes...
of five immunoglobulin-like (Ig) domains followed by two fibronectintypeIII (FNIII) domains. The different domains of NCAM have been shown to have different...
characterized by their extracellular domains containing Ig-like domains. The Ig domains are then followed by FibronectintypeIIIdomain repeats and IgSFs are anchored...
120 fibronectin-III-type and Ig-typedomains. In the serine proteases, a gene duplication event has led to the formation of a two β-barrel domain enzyme...
adhesion molecule with multiple immunoglobulin-like C2-typedomains and fibronectintype-IIIdomains. This ankyrin-binding protein is involved in neuron-neuron...
"Recruitment of the RNA helicase RHAU to stress granules via a unique RNA-binding domain". The Journal of Biological Chemistry. 283 (50): 35186–35198. doi:10.1074/jbc...
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