Protein-coding gene in the species Homo sapiens
LRFN4 Identifiers Aliases LRFN4 , FIGLER6, SALM3, SALM3., leucine rich repeat and fibronectin type III domain containing 4External IDs OMIM: 612810; MGI: 2385612; HomoloGene: 36415; GeneCards: LRFN4; OMA:LRFN4 - orthologs Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q13.2 Start 66,856,647 bp[1] End 66,860,475 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 A Start 4,661,813 bp[2] End 4,665,695 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence right hemisphere of cerebellum mucosa of transverse colon apex of heart right frontal lobe anterior cingulate cortex right uterine tube stromal cell of endometrium decidua amygdala
Top expressed in ventricular zone epiblast hand ganglionic eminence yolk sac superior frontal gyrus primary visual cortex external carotid artery dentate gyrus of hippocampal formation granule cell internal carotid artery
More reference expression data
BioGPS
Gene ontology Molecular function Cellular component
cell surface
membrane
integral component of membrane
plasma membrane
extracellular space
glutamatergic synapse
GABA-ergic synapse
integral component of postsynaptic density membrane Biological process
axonogenesis
regulation of postsynaptic density assembly
synaptic membrane adhesion
regulation of presynapse assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) NP_076941
Location (UCSC) Chr 11: 66.86 – 66.86 Mb Chr 19: 4.66 – 4.67 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Leucine rich repeat and fibronectin type III domain containing 4 is a protein that in humans is encoded by the LRFN4 gene.[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000173621 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045045 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^
"Entrez Gene: Leucine rich repeat and fibronectin type III domain containing 4". Retrieved 2016-10-17 .
Last Update: 2023-03-04T00:31:34Z
Leucine rich repeat and fibronectin type III domain containing 4 is a protein that in humans is encoded by the LRFN4 gene. Fibronectin type III domain...
Word Count : 146
Last Update: 2024-03-28T22:58:07Z
LRFN4 encoding protein Leucine rich repeat and fibronectin type III domain containing 4 MADD: MAP kinase-activating death domain protein MEN1: Multiple...
Word Count : 1930
Last Update: 2024-05-25T16:28:07Z
rich repeat domain (L2, residues 311–470), three fibronectin type III domains ; FnIII -1 (residues 471–595), FnIII -2 (residues 596–808) and FnIII -3 (residues...
Word Count : 3785
Last Update: 2023-12-21T09:42:17Z
It belongs to the small leucine -rich proteoglycan (SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan (GAG)...
Word Count : 1949
Last Update: 2024-05-27T11:00:36Z
as 'D' and changes depending upon the hydration state of the aggregate). In each D-period repeat of the microfibril, there is a part containing five molecules...
Word Count : 7740
Last Update: 2024-02-19T08:42:52Z
2002). "Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes". Gene. 297 (1–2): 79–83. doi:10.1016/S0378-1119(02)00828-4 . PMID 12384288...
Word Count : 4564
Last Update: 2024-06-09T04:52:47Z
Mokas S, Mazroui R, Côté J (October 2008). "TDRD3, a novel Tudor domain -containing protein, localizes to cytoplasmic stress granules". Human Molecular...
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