Type I cytokine receptors are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokines with four α-helical strands. These receptors are also known under the name hemopoietin receptors, and share a common amino acid motif (WSXWS) in the extracellular portion adjacent to the cell membrane. Members of the type I cytokine receptor family comprise different chains, some of which are involved in ligand/cytokine interaction and others that are involved in signal transduction.
The common cytokine-binding domain is related to the Fibronectin type III domain.
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TypeIcytokinereceptors are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokines with four α-helical strands...
Cytokinereceptors are receptors that bind to cytokines. In recent years, the cytokinereceptors have come to demand the attention of more investigators...
Type II cytokinereceptors, also commonly known as class II cytokinereceptors, are transmembrane proteins that are expressed on the surface of certain...
Leptin receptor, also known as LEP-R or OB-R, is a typeIcytokinereceptor, a protein that in humans is encoded by the LEPR gene. LEP-R functions as a...
member of the class of tall cytokinereceptors. It forms one subunit of the typeIcytokinereceptor within the IL-6 receptor family. It is often referred...
interleukin receptors: IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. The γc glycoprotein is a member of the typeIcytokinereceptor family expressed...
the typeIcytokinereceptor family. This protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with...
response to physical exercise. IL-6 signals through a cell-surface typeIcytokinereceptor complex consisting of the ligand-binding IL-6Rα chain (CD126),...
found on the surface of EPO responding cells. It is a member of the cytokinereceptor family. EpoR pre-exists as dimers. These dimers were originally thought...
(ALL). Cytokine signals are mediated through specific receptor complexes, the components of which are mostly members of the typeIcytokinereceptor family...
various stromal cells; a given cytokine may be produced by more than one type of cell. They act through cell surface receptors and are especially important...
The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses...
An inflammatory cytokine or proinflammatory cytokine is a type of signaling molecule (a cytokine) that is secreted from immune cells like helper T cells...
toll like receptors (TLRs) and C-type lectin receptors (CLRs). Cytoplasmic PRRs include NOD-like receptors (NLRs) and RIG-I-like receptors (RLRs). PRRs...
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