In molecular biology, an exonic splicing enhancer (ESE) is a DNA sequence motif consisting of 6 bases within an exon that directs, or enhances, accurate splicing of heterogeneous nuclear RNA (hnRNA) or pre-mRNA into messenger RNA (mRNA).
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biology, an exonicsplicingenhancer (ESE) is a DNA sequence motif consisting of 6 bases within an exon that directs, or enhances, accurate splicing of heterogeneous...
proteins bind to a juxtaposed exonicsplicingenhancer/exonicsplicing silencer element to regulate HIV-1 tat exon 2 splicing". The Journal of Biological...
splicing silencer (ISS), Exonicsplicingenhancer (ESE), and Exonicsplicing silencer (ESSE3). Solution structure of Intronic splicing silencer and its interaction...
that will negatively affect the core splicing machinery. Exonicsplicing silencers work by inhibiting the splicing of pre-mRNA strands or promoting exon...
gene is not expressed. The mRNA of C7orf50 is predicted to have exonicsplicingenhancers, in which SR proteins can bind, at bp positions 45 (SRSF1 (IgM-BRCA1))...
European School of Economics European Society of Endocrinology Exonicsplicingenhancer Exoskeletal engine Extensible Storage Engine Massachusetts Department...
competing with each other to bind to exonicsplicingenhancers. Some evidence suggests that selection of the mRNA splicing variant depends upon the relative...
Zahler AM (January 1998). "Specific binding of an exonicsplicingenhancer by the pre-mRNA splicing factor SRp55". RNA. 4 (1): 11–23. PMC 1369592. PMID 9436904...
may serve as regulatory sequences in the pre-mRNA as exonicsplicingenhancers or exonicsplicing silencers. Untranslated regions (UTRs) are sections of...
the fibronectin EDA exon alternative splicing. Cooperative role of the exonicenhancer element and the 5' splicing site". FEBS Letters. 437 (1–2): 137–141...
gene exon 10 associated with FTDP-17 alter the activity of an exonicsplicingenhancer to interact with Tra2 beta". J. Biol. Chem. 278 (21): 18997–9007...
(2004). "Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonicsplicingenhancer in exon 10 of tau pre-mRNA". Genes Cells. 9 (2): 121–30. doi:10...
segment 7 transcript. For example, the splice site, polypyrimidine tract, branch point, and ASF/SF2 exonicenhancer binding sites are expected to be more...
molecules that regulate splicing (e.g. spliceenhancers, splice suppressors) from binding to pre-mRNA, altering patterns of splicing. Common incorrect uses...
by a tRNA splicing endonuclease. The exons are then linked together by a second protein, the tRNA splicing ligase. Note that self-splicing introns are...
two different chromosomes. Trans-splicing is very common in C. elegans A splice donor site being joined to a splice acceptor site further upstream in...
PMID 16303743. Ramser J, Abidi FE, Burckle CA, et al. (2005). "A unique exonicspliceenhancer mutation in a family with X-linked mental retardation and epilepsy...
abundance of alternative splicing, which occurs in most human genes, and the specificity in which splicing is carried out in vivo. Splicing is distinctly conducted...
Serine/arginine-rich splicing factor 7 (SRSF7) also known as splicing factor, arginine/serine-rich 7 (SFRS7) or splicing factor 9G8 is a protein that...
of disease-causing mutations affect RNA splicing. Such mutations frequently affect Exonicsplicingenhancers, regions of pre-mRNA that recruit the spliceosome...
chromosome at Xp11.23 in humans. RBM10 is a regulator of alternative splicing. Alternative splicing is a process associated with gene expression to produce multiple...
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