SFRS6 information

SRSF6
Identifiers
Aliases	SRSF6, B52, HEL-S-91, SFRS6, SRP55, serine/arginine-rich splicing factor 6, serine and arginine rich splicing factor 6
External IDs	OMIM: 601944; MGI: 1915246; HomoloGene: 110783; GeneCards: SRSF6; OMA:SRSF6 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	43,466,046 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	162,779,041 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; body of pancreas; ; right lobe of thyroid gland; ; right adrenal cortex; ; right ovary; ; left lobe of thyroid gland; ; left ovary; ; germinal epithelium; ; ventricular zone; ; left adrenal gland;
	Top expressed in
	medullary collecting duct; ; abdominal wall; ; renal corpuscle; ; endocardial cushion; ; somite; ; superior cervical ganglion; ; epiblast; ; ventricular zone; ; dermis; ; Gonadal ridge;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding; nucleic acid binding; pre-mRNA binding;
Cellular component	nuclear speck; nucleus; nucleoplasm;
Biological process	mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; negative regulation of keratinocyte differentiation; positive regulation of epithelial cell proliferation involved in lung morphogenesis; mRNA processing; negative regulation of cell death; regulation of alternative mRNA splicing, via spliceosome; mRNA export from nucleus; negative regulation of mRNA splicing, via spliceosome; regulation of wound healing; mRNA splice site selection; regulation of keratinocyte proliferation; alternative mRNA splicing, via spliceosome; mRNA 3'-end processing; negative regulation of gene expression; RNA splicing; response to insulin; RNA export from nucleus; negative regulation of type B pancreatic cell apoptotic process; mRNA cis splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	6431
	67996
	ENSG00000124193
	ENSMUSG00000016921
	Q13247
	Q3TWW8
	NM_006275
	NM_026499
	NP_006266
	NP_080775
	Wikidata
View/Edit Human	View/Edit Mouse

Splicing factor, arginine/serine-rich 6 is a protein that in humans is encoded by the SFRS6 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000124193 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000016921 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Screaton GR, Cáceres JF, Mayeda A, Bell MV, Plebanski M, Jackson DG, Bell JI, Krainer AR (September 1995). "Identification and characterization of three members of the human SR family of pre-mRNA splicing factors". The EMBO Journal. 14 (17): 4336–49. doi:10.1002/j.1460-2075.1995.tb00108.x. PMC 394518. PMID 7556075.
^ "Entrez Gene: SFRS6 splicing factor, arginine/serine-rich 6".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000124193 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000016921 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7556075-5] Screaton GR, Cáceres JF, Mayeda A, Bell MV, Plebanski M, Jackson DG, Bell JI, Krainer AR (September 1995). "Identification and characterization of three members of the human SR family of pre-mRNA splicing factors". The EMBO Journal. 14 (17): 4336–49. doi:10.1002/j.1460-2075.1995.tb00108.x. PMC 394518. PMID 7556075.

[entrez-6] "Entrez Gene: SFRS6 splicing factor, arginine/serine-rich 6".

SFRS6 information

and 3 Related for: SFRS6 information

SFRS6

SR protein

RNA recognition motif