RNA-binding motif 10 is a protein that is encoded by the RBM10 gene.[5][6][7][8] This gene maps on the X chromosome at Xp11.23 in humans. RBM10 is a regulator of alternative splicing.[9][10][11] Alternative splicing is a process associated with gene expression to produce multiple protein isoforms from a single gene, thereby creating functional diversity and cellular complexity.[12] RBM10 influences the expression of many genes,[9][10][13][14][15] participating in various cellular processes and pathways such as cell proliferation and apoptosis.[10][16] Its mutations are associated with various human diseases[17][18][19][20][21][22] such as TARP syndrome,[22][17] an X-linked congenital disorder in males resulting in pre‐ or postnatal lethality, and various cancers in adults.[18][19]
^ abcGRCh38: Ensembl release 89: ENSG00000182872 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000031060 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Cite error: The named reference Nagase-1995 was invoked but never defined (see the help page).
^Cite error: The named reference Coleman-1996 was invoked but never defined (see the help page).
^Cite error: The named reference Thiselton-2002 was invoked but never defined (see the help page).
^Cite error: The named reference Inoue-1996 was invoked but never defined (see the help page).
^ abCite error: The named reference Wang-2013 was invoked but never defined (see the help page).
^ abcCite error: The named reference Bechara-2013 was invoked but never defined (see the help page).
^Cite error: The named reference Inoue-2014 was invoked but never defined (see the help page).
^Cite error: The named reference Yang-2016 was invoked but never defined (see the help page).
^Cite error: The named reference Sutherland-2017 was invoked but never defined (see the help page).
^Cite error: The named reference Sun-2017 was invoked but never defined (see the help page).
^Cite error: The named reference Collins-2017 was invoked but never defined (see the help page).
^Cite error: The named reference Loiselle-2017 was invoked but never defined (see the help page).
^ abCite error: The named reference Johnston-2010 was invoked but never defined (see the help page).
^ abCite error: The named reference Imielinski-2012 was invoked but never defined (see the help page).
^ abCite error: The named reference Seiler-2018 was invoked but never defined (see the help page).
^Cite error: The named reference Cieply-2015 was invoked but never defined (see the help page).
^Cite error: The named reference Coomer-2019 was invoked but never defined (see the help page).
^ abGorlin RJ, Cervenka J, Anderson RC, Sauk JJ, Bevis WD (February 1970). "Robin's syndrome. A probably X-linked recessive subvariety exhibiting persistence of left superior vena cava and atrial septal defect". American Journal of Diseases of Children. 119 (2): 176–8. doi:10.1001/archpedi.1970.02100050178020. PMID 5410571.
10 is a protein that is encoded by the RBM10 gene. This gene maps on the X chromosome at Xp11.23 in humans. RBM10 is a regulator of alternative splicing...
correlation between the expression of X-chromosome RBM genes (RBMX, RBM3, RBM10) and the proapoptotic Bax gene in human breast cancer". Journal of Cellular...
Global Information
