C7orf50 information

C7orf50
Identifiers
Aliases	C7orf50, YCR016W, chromosome 7 open reading frame 50
External IDs	MGI: 1920462; HomoloGene: 49901; GeneCards: C7orf50; OMA:C7orf50 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	1,138,260 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	139,446,282 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; right coronary artery; ; cingulate gyrus; ; anterior cingulate cortex; ; right frontal lobe; ; amygdala; ; sural nerve; ; apex of heart; ; popliteal artery; ; tibial arteries;
	Top expressed in
	yolk sac; ; primitive streak; ; aortic valve; ; ascending aorta; ; otolith organ; ; utricle; ; epiblast; ; oocyte; ; primary oocyte; ; secondary oocyte;
	More reference expression data
	n/a
Orthologs
	84310
	73212
	ENSG00000146540
	ENSMUSG00000053553
	Q9BRJ6
	Q9CXL3
NM_001134395; NM_001134396; NM_032350; NM_001318252; NM_001350968;
	NM_001350969; NM_001350970
	NM_028469
NP_001127867; NP_001127868; NP_001305181; NP_115726; NP_001337897;
	NP_001337898; NP_001337899
	NP_082745
	Wikidata
View/Edit Human	View/Edit Mouse

C7orf50 (Chromosome 7, Open Reading Frame 50) is a gene in humans (Homo sapiens) that encodes a protein known as C7orf50 (uncharacterized protein C7orf50). This gene is ubiquitously expressed in the kidneys, brain, fat, prostate, spleen, among 22 other tissues and demonstrates low tissue specificity.^[5]^[6] C7orf50 is conserved in chimpanzees, Rhesus monkeys, dogs, cows, mice, rats, and chickens, along with 307 other organisms from mammals to fungi.^[7] This protein is predicted to be involved with the import of ribosomal proteins into the nucleus to be assembled into ribosomal subunits as a part of rRNA processing.^[8]^[9] Additionally, this gene is predicted to be a microRNA (miRNA) protein coding host gene, meaning that it may contain miRNA genes in its introns and/or exons.^[10]^[11]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000146540 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000053553 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "C7orf50 chromosome 7 open reading frame 50 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-04-29.
^ "C7orf50 protein expression summary - The Human Protein Atlas". www.proteinatlas.org. Retrieved 2020-04-29.
^ Cite error: The named reference :7 was invoked but never defined (see the help page).
^ Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P (2002). "The Transport of Molecules between the Nucleus and the Cytosol". Molecular Biology of the Cell (4th ed.). Garland Science.
^ Cite error: The named reference :8 was invoked but never defined (see the help page).
^ Boivin V, Deschamps-Francoeur G, Scott MS (March 2018). "Protein coding genes as hosts for noncoding RNA expression". Seminars in Cell & Developmental Biology. 75: 3–12. doi:10.1016/j.semcdb.2017.08.016. PMID 28811264.
^ HUGO Gene Nomenclature Committee. "MicroRNA protein coding host genes". GeneNames. Archived from the original on 2018-11-21. Retrieved 2020-04-29.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000146540 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000053553 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[:0-5] "C7orf50 chromosome 7 open reading frame 50 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-04-29.

[:9-6] "C7orf50 protein expression summary - The Human Protein Atlas". www.proteinatlas.org. Retrieved 2020-04-29.

[:7-7] Cite error: The named reference :7 was invoked but never defined (see the help page).

[8] Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P (2002). "The Transport of Molecules between the Nucleus and the Cytosol". Molecular Biology of the Cell (4th ed.). Garland Science.

[:8-9] Cite error: The named reference :8 was invoked but never defined (see the help page).

[10] Boivin V, Deschamps-Francoeur G, Scott MS (March 2018). "Protein coding genes as hosts for noncoding RNA expression". Seminars in Cell & Developmental Biology. 75: 3–12. doi:10.1016/j.semcdb.2017.08.016. PMID 28811264.

[11] HUGO Gene Nomenclature Committee. "MicroRNA protein coding host genes". GeneNames. Archived from the original on 2018-11-21. Retrieved 2020-04-29.