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Epigenetics of schizophrenia information


The epigenetics of schizophrenia is the study of how inherited epigenetic changes are regulated and modified by the environment and external factors and how these changes influence the onset and development of, and vulnerability to, schizophrenia. Epigenetics concerns the heritability of those changes, too. Schizophrenia is a debilitating and often misunderstood disorder that affects up to 1% of the world's population.[1] Although schizophrenia is a heavily studied disorder, it has remained largely impervious to scientific understanding; epigenetics offers a new avenue for research, understanding, and treatment.

  1. ^ Roth TL, Lubin FD, Sodhi M, Kleinman JE (September 2009). "Epigenetic mechanisms in schizophrenia". Biochimica et Biophysica Acta (BBA) – General Subjects. 1790 (9): 869–877. doi:10.1016/j.bbagen.2009.06.009. PMC 2779706. PMID 19559755.

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Epigenetics of schizophrenia

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The epigenetics of schizophrenia is the study of how inherited epigenetic changes are regulated and modified by the environment and external factors and...

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Schizophrenia

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Schizophrenia is a mental disorder characterized by reoccurring episodes of psychosis that are correlated with a general misperception of reality. Other...

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Behavioral epigenetics

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Behavioral epigenetics is the field of study examining the role of epigenetics in shaping animal and human behavior. It seeks to explain how nurture shapes...

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Risk factors of schizophrenia

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for schizophrenia in a few individuals. One such CNV is found in DiGeorge syndrome, which carries a 25-30% lifetime risk of schizophrenia. Epigenetics may...

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Epigenetics of physical exercise

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Epigenetics of physical exercise is the study of epigenetic modifications to the cell genome resulting from physical exercise. Environmental factors,...

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Epigenetic therapy

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treating diseases by targeting epigenetic mechanisms such as DNA methylation and histone modifications. Epigenetics is the study of changes in gene expression...

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Epigenetics of bipolar disorder

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Epigenetics of bipolar disorder is the effect that epigenetics has on triggering and maintaining bipolar disorder. Bipolar disorder is a chronic mood disorder...

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Developmental origins of health and disease

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cardiology". Journal of Cardiology. 76 (1): 14–17. doi:10.1016/j.jjcc.2020.02.003. PMID 32115330. S2CID 211726894. "What is Epigenetics?". Centers for Disease...

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Nutritional epigenetics

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obesity, schizophrenia, depression, and addiction. Biologists Randy Jirtle and Robert A. Waterland became early pioneers of nutritional epigenetics after...

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Anhedonia

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2011). "Sex differences in epigenetic mechanisms may underlie risk and resilience for mental health disorders". Epigenetics. 6 (7): 857–61. doi:10.4161/epi...

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Schizophrenia Research Foundation

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Schizophrenia Research Foundation (SCARF) was founded in 1984 with the primary objective of providing quality care and rehabilitation to those suffering...

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Epigenetics in learning and memory

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memory and addiction". Epigenetics. 6 (6): 671–4. doi:10.4161/epi.6.6.15905. PMC 3142366. PMID 21586900. Lubin FD (2011). "Epigenetic Mechanisms: Critical...

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Moinak Banerjee

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genetic, immunogenetics, pharmacogenetics, and epigenetics of complex diseases such as Epilepsy, Schizophrenia, Autism, Cerebral stroke (Aneurysm), Dementia...

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Epigenetics of autism

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factors. More research is identifying ways in which epigenetics is linked to autism. Epigenetics generally refers to the ways in which chromatin structure...

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Epigenetics in forensic science

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Epigenetics in forensic science is the application of epigenetics to solving crimes. Forensic science has been using DNA as evidence since 1984, however...

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Reelin

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trans-methylation to cytosine methylation: evolution of the methylation hypothesis of schizophrenia". Epigenetics. 4 (3): 144–9. doi:10.4161/epi.4.3.8534. PMID 19395859...

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Imprinted brain hypothesis

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hypothesis in evolutionary psychology regarding the causes of autism spectrum and schizophrenia spectrum disorders, first presented by Bernard Crespi and...

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Irving Gottesman

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2016) was an American professor of psychology who devoted most of his career to the study of the genetics of schizophrenia. He wrote 17 books and more than...

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Regulation of gene expression

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DNA methylation at CpG sites, and (3) epigenetic downregulation or upregulation of microRNAs. (See Epigenetics of cocaine addiction for some details.)...

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Epiphenotyping

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studies (EWAS) are both approaches used in epigenetics research, however they focus on distinct aspects of epigenetic data analysis. Epiphenotyping is focused...

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Toxoplasmosis

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with schizophrenia for T. gondii antibodies, associations between T. gondii and schizophrenia have been found prior to the onset of schizophrenia symptoms...

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Refrigerator mother theory

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coined around 1950 as a label for mothers or fathers of children diagnosed with autism or schizophrenia. Both terms are now regarded as stigmatizing, and...

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Conditions comorbid to autism spectrum disorders

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colloquium: Comparative genomics of autism and schizophrenia". Proceedings of the National Academy of Sciences of the United States of America. 107 (Suppl 1):...

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Epigenetic regulation of neurogenesis

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Epigenetic regulation of neurogenesis is the role that epigenetics (hertitable characteristics that do not involve changes in DNA sequence) plays in the...

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Interleukin 6

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of epigenetic modification by IL-6 has been proposed as a mechanism in the pathology of schizophrenia through the hypermethylation and repression of the...

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Transgenerational trauma

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2011). "Epigenetic marking of the BDNF gene by early-life adverse experiences". Hormones and Behavior. Special Issue: Behavioral Epigenetics. 59 (3):...

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