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Chlorprothixene information


Chlorprothixene
Clinical data
Trade namesTruxal, others
AHFS/Drugs.comMicromedex Detailed Consumer Information
Routes of
administration
Oral, intramuscular injection
Drug classTypical antipsychotic
ATC code
  • N05AF03 (WHO)
Legal status
Legal status
  • BR: Class C1 (Other controlled substances)[1]
  • In general: ℞ (Prescription only)
Pharmacokinetic data
MetabolismHepatic
Elimination half-life8–12 hours
ExcretionFeces, urine
Identifiers
IUPAC name
  • (Z)-3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethyl-propan-1-amine
CAS Number
  • 113-59-7 checkY
PubChem CID
  • 667467
DrugBank
  • DB01239 checkY
ChemSpider
  • 580849 checkY
UNII
  • 9S7OD60EWP
KEGG
  • D00790 checkY
ChEBI
  • CHEBI:50931 checkY
ChEMBL
  • ChEMBL908 checkY
CompTox Dashboard (EPA)
  • DTXSID4022810 Edit this at Wikidata
ECHA InfoCard100.003.666 Edit this at Wikidata
Chemical and physical data
FormulaC18H18ClNS
Molar mass315.86 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • Clc2cc1C(\c3c(Sc1cc2)cccc3)=C/CCN(C)C
InChI
  • InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3/b14-7- checkY
  • Key:WSPOMRSOLSGNFJ-AUWJEWJLSA-N checkY
  (verify)

Chlorprothixene, sold under the brand name Truxal among others, is a typical antipsychotic of the thioxanthene group.

  1. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.

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MDMA

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LSD

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Mevidalen Antagonists Typical antipsychotics: Butaclamol Chlorpromazine Chlorprothixene Flupentixol (flupenthixol) (+melitracen) Fluphenazine Loxapine Perphenazine...

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Thioxanthene

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derivatives of thioxanthene used clinically as antipsychotics include: Chlorprothixene (Cloxan, Taractan, Truxal) Clopenthixol (Sordinol) Flupenthixol (Depixol...

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Brazilian Controlled Drugs and Substances Act

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Quetiapine

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"Postmortem femoral blood reference concentrations of aripiprazole, chlorprothixene, and quetiapine". Journal of Analytical Toxicology. 39 (1): 41–44....

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Lundbeck

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Antihistamine

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Tiotixene

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is chemically related to other typical neuroleptic agents such as chlorprothixene, clopenthixol, flupenthixol, and zuclopenthixol. Tiotixene also shares...

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Typical antipsychotic

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typical antipsychotics organized by potency, see below: Chlorpromazine Chlorprothixene Levomepromazine Mesoridazine Periciazine Promazine Thioridazine† (withdrawn...

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Buspirone

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Cyclobenzaprine

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Trifluoperazine

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schizophrenia than lower-potency antipsychotics like chlorpromazine, chlorprothixene, thioridazine and levomepromazine, but trifluoperazine appears to cause...

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Serotonin

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Tramadol

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Fluoxetine

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Psychedelic drug

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List of dopaminergic drugs

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Azaperone • Benperidol • Bromperidol • Clopenthixol • Chlorpromazine • Chlorprothixene • Droperidol • Flupentixol • Fluphenazine • Fluspirilene • Haloperidol •...

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Flupentixol

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having already developed the thioxanthene derivatives clopenthixol and chlorprothixene. By 1965 the promising agent flupenthixol had been developed and trialled...

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Pantothenic acid

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Bupropion

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Cannabidiol

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Tardan

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Tardan may refer to: Chlorprothixene, a pharmaceutical Tardan, Iran, a village in Markazi Province, Iran This disambiguation page lists articles associated...

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Metoclopramide

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Mevidalen Antagonists Typical antipsychotics: Butaclamol Chlorpromazine Chlorprothixene Flupentixol (flupenthixol) (+melitracen) Fluphenazine Loxapine Perphenazine...

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Nitrous oxide

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Levosulpiride

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