Antihistamine used to treat allergies
Not to be confused with Chlorphenacemide.
Chlorphenamine Trade names Chlor-Trimeton; Piriton; Chlor-Tripolon AHFS/Drugs.com Monograph MedlinePlus a682543 Pregnancy category Routes of administration Oral, Intravenous, Intramuscular, Subcutaneous ATC code Legal status
AU : S3 (Pharmacist only)
UK : P (Pharmacy medicines)
US : OTC
Bioavailability 25 to 50% Protein binding 72% Metabolism Liver (CYP2D6) Elimination half-life 13.9–43.4 hours[1] Excretion Kidney
3-(4-Chlorophenyl)-N ,N -dimethyl-3-(pyridin-2-yl)-propan-1-amine
CAS Number 132-22-9 N PubChem CID IUPHAR/BPS DrugBank DB01114 Y ChemSpider 2624 Y UNII KEGG D07398 Y ChEBI CHEBI:52010 Y ChEMBL ChEMBL505 Y CompTox Dashboard (EPA ) DTXSID0022804 ECHA InfoCard 100.004.596 Formula C 16 H 19 Cl N 2 Molar mass 274.79 g·mol−1 3D model (JSmol) Solubility in water 0.55 g/100 mL, liquid mg/mL (20 °C)
Clc1ccc(cc1)C(c2ncccc2)CCN(C)C
InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3
Y Key:SOYKEARSMXGVTM-UHFFFAOYSA-N
Y
N Y (what is this?) (verify)
Chlorphenamine (CP , CPM ), also known as chlorpheniramine , is an antihistamine used to treat the symptoms of allergic conditions such as allergic rhinitis (hay fever).[2] It is taken orally (by mouth).[2] The medication takes effect within two hours and lasts for about 4–6 hours.[2] It is a first-generation antihistamine and works by blocking the H1 receptor.[2]
Common side effects include sleepiness, restlessness, and weakness. Other side effects may include dry mouth and wheeziness.[2]
Chlorpheniramine was patented in 1948 and came into medical use in 1949.[3] It is available as a generic medication and over the counter.[2] [4]
^ Cite error: The named reference pmid7648771
was invoked but never defined (see the help page).
^ a b c d e f "Chlorpheniramine". Drugs.com . American Society of Health-System Pharmacists. 26 July 2023. Archived from the original on 20 August 2023. Retrieved 20 August 2023 .
^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery . John Wiley & Sons. p. 546. ISBN 9783527607495 .
^ "Over-the-Counter Medicines for Allergies". HealthLink BC . Archived from the original on 15 July 2019. Retrieved 15 July 2019 .
Last Update: 2024-04-05T05:21:37Z
Chlorphenamine (CP, CPM), also known as chlorpheniramine, is an antihistamine used to treat the symptoms of allergic conditions such as allergic rhinitis...
Word Count : 1711
Last Update: 2024-02-02T03:15:45Z
its potency 20-fold. Halogenated derivatives of pheniramine include chlorphenamine , brompheniramine, dexchlorpheniramine, dexbrompheniramine, and zimelidine...
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Last Update: 2024-03-30T18:18:47Z
injury. Tricyclic antidepressants like imipramine. Antihistamines like chlorphenamine . Decongestants like ephedrine and phenylephrine. These medications tighten...
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Last Update: 2024-03-23T21:46:16Z
P star") represents pentamethylcyclopentadienyl, the C 5Me 5 ligand Chlorphenamine , a first-generation alkylamine antihistamine Creatine phosphate, a chemical...
Word Count : 847
Last Update: 2022-12-31T09:23:17Z
Brompheniramine R06AB02 Dexchlorpheniramine R06AB03 Dimetindene R06AB04 Chlorphenamine R06AB05 Pheniramine R06AB06 Dexbrompheniramine R06AB07 Talastine R06AB51...
Word Count : 355
Last Update: 2024-04-28T22:46:05Z
196 CAR-302,282 CAR-302,368 CAR-302,537 CAR-302,668 Chloropyramine Chlorphenamine Clemastine CS-27349 Cyclizine Cyproheptadine Dicycloverine Dimenhydrinate...
Word Count : 14661
Last Update: 2024-04-02T05:19:08Z
Buclizine Captodiame Carbinoxamine Chlorcyclizine Chloropyramine Chlorothen Chlorphenamine Chlorphenoxamine Cinnarizine Clemastine Clobenzepam Clocinizine Cloperastine...
Word Count : 6534
Last Update: 2024-04-18T12:46:14Z
196 CAR-302,282 CAR-302,368 CAR-302,537 CAR-302,668 Chloropyramine Chlorphenamine Clemastine CS-27349 Cyclizine Cyproheptadine Dicycloverine Dimenhydrinate...
Word Count : 5352
Last Update: 2024-04-26T11:20:50Z
Buclizine Captodiame Carbinoxamine Chlorcyclizine Chloropyramine Chlorothen Chlorphenamine Chlorphenoxamine Cinnarizine Clemastine Clobenzepam Clocinizine Cloperastine...
Word Count : 2670
Last Update: 2024-04-28T03:29:56Z
Oxaprotiline Setiptiline Others: Antihistamines (e.g., brompheniramine, chlorphenamine , pheniramine, tripelennamine) Antipsychotics (e.g., loxapine, ziprasidone)...
Word Count : 17671
Last Update: 2024-03-22T14:05:29Z
Antihistamines (first-generation) (e.g., brompheniramine, buclizine, captodiame, chlorphenamine (chlorpheniramine), cinnarizine, clemastine, cyproheptadine, dimenhydrinate...
Word Count : 1707
Last Update: 2024-04-19T17:28:13Z
Buclizine Captodiame Carbinoxamine Chlorcyclizine Chloropyramine Chlorothen Chlorphenamine Chlorphenoxamine Cinnarizine Clemastine Clobenzepam Clocinizine Cloperastine...
Word Count : 3708
Last Update: 2024-04-17T21:28:25Z
196 CAR-302,282 CAR-302,368 CAR-302,537 CAR-302,668 Chloropyramine Chlorphenamine Clemastine CS-27349 Cyclizine Cyproheptadine Dicycloverine Dimenhydrinate...
Word Count : 5328
Last Update: 2024-04-20T06:44:07Z
Buclizine Captodiame Carbinoxamine Chlorcyclizine Chloropyramine Chlorothen Chlorphenamine Chlorphenoxamine Cinnarizine Clemastine Clobenzepam Clocinizine Cloperastine...
Word Count : 8657
Last Update: 2024-04-28T09:43:15Z
196 CAR-302,282 CAR-302,368 CAR-302,537 CAR-302,668 Chloropyramine Chlorphenamine Clemastine CS-27349 Cyclizine Cyproheptadine Dicycloverine Dimenhydrinate...
Word Count : 15751
Last Update: 2024-02-15T12:46:15Z
18-Methoxycoronaridine BMY-13980 Butaclamol Caramiphen Carvotroline Chlorphenamine (chlorpheniramine) Chlorpromazine Cinnarizine Cinuperone Clocapramine...
Word Count : 7843
Last Update: 2023-11-20T12:54:52Z
Antihistamines (first-generation) (e.g., brompheniramine, buclizine, captodiame, chlorphenamine (chlorpheniramine), cinnarizine, clemastine, cyproheptadine, dimenhydrinate...
Word Count : 4232
Last Update: 2024-04-20T10:14:37Z
196 CAR-302,282 CAR-302,368 CAR-302,537 CAR-302,668 Chloropyramine Chlorphenamine Clemastine CS-27349 Cyclizine Cyproheptadine Dicycloverine Dimenhydrinate...
Word Count : 6249
Last Update: 2024-04-27T19:19:28Z
Oxaprotiline Setiptiline Others: Antihistamines (e.g., brompheniramine, chlorphenamine , pheniramine, tripelennamine) Antipsychotics (e.g., loxapine, ziprasidone)...
Word Count : 7230
Last Update: 2024-03-08T02:40:07Z
Buclizine Captodiame Carbinoxamine Chlorcyclizine Chloropyramine Chlorothen Chlorphenamine Chlorphenoxamine Cinnarizine Clemastine Clobenzepam Clocinizine Cloperastine...
Word Count : 2340
Last Update: 2024-04-02T23:59:05Z
Buclizine Captodiame Carbinoxamine Chlorcyclizine Chloropyramine Chlorothen Chlorphenamine Chlorphenoxamine Cinnarizine Clemastine Clobenzepam Clocinizine Cloperastine...
Word Count : 4889
Last Update: 2024-04-08T14:52:49Z
196 CAR-302,282 CAR-302,368 CAR-302,537 CAR-302,668 Chloropyramine Chlorphenamine Clemastine CS-27349 Cyclizine Cyproheptadine Dicycloverine Dimenhydrinate...
Word Count : 5149
Last Update: 2024-04-07T05:39:16Z
196 CAR-302,282 CAR-302,368 CAR-302,537 CAR-302,668 Chloropyramine Chlorphenamine Clemastine CS-27349 Cyclizine Cyproheptadine Dicycloverine Dimenhydrinate...
Word Count : 4203
Last Update: 2024-04-06T20:33:11Z
Antihistamines (first-generation) (e.g., brompheniramine, buclizine, captodiame, chlorphenamine (chlorpheniramine), cinnarizine, clemastine, cyproheptadine, dimenhydrinate...
Word Count : 2618
Last Update: 2024-03-04T05:59:29Z
first-generation antihistamines (brompheniramine, promethazine, diphenhydramine, chlorphenamine ), beta blockers, and alcohol. When combined therapy is contemplated...
Word Count : 3963
Last Update: 2024-01-22T04:39:46Z
196 CAR-302,282 CAR-302,368 CAR-302,537 CAR-302,668 Chloropyramine Chlorphenamine Clemastine CS-27349 Cyclizine Cyproheptadine Dicycloverine Dimenhydrinate...
Word Count : 3073
Last Update: 2024-04-28T09:40:34Z
Antihistamines (first-generation) (e.g., brompheniramine, buclizine, captodiame, chlorphenamine (chlorpheniramine), cinnarizine, clemastine, cyproheptadine, dimenhydrinate...
Word Count : 11355