Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide (NO), a key chemical involved in normal endothelial function and, by extension, cardiovascular health.
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Asymmetricdimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification...
through agmatine, citrulline, and glutamate). The presence of asymmetricdimethylarginine (ADMA), a close relative, inhibits the nitric oxide reaction;...
through the breakdown of proline or glutamine/glutamate from asymmetricdimethylarginine via DDAH Citrulline is made from ornithine and carbamoyl phosphate...
the kidney. Asymmetrically methylated forms however are toxic and must first be broken down. This step requires the enzyme dimethylarginine dimethylaminohydrolase...
groups on one terminal nitrogen (asymmetricdimethylarginine) or one on both nitrogens (symmetric dimethylarginine), by protein arginine methyltransferases...
the diminishing of nitric oxide, often due to high levels of asymmetricdimethylarginine, which interfere with the normal L-arginine-stimulated nitric...
dictionary. SDMA may refer to: Symmetric dimethylarginine, an exogenous isomer of asymmetricdimethylarginine (ADMA) that is used as a renal function tracer/biomarker...
isoforms). The enzyme degrades methylarginines, specifically asymmetricdimethylarginine (ADMA) and NG-monomethyl-L-arginine (MMA). The methylarginines...
(2002). "Relationship between Salt Intake, Nitric Oxide and AsymmetricDimethylarginine and Its Relevance to Patients with End-Stage Renal Disease −"...
growth. Finally, altered methylation may catalyse l-arginine to asymmetricdimethylarginine, which is known to increase the risk of vascular disease. Homocystinuria...
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