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Neuronal calcium sensor information


Neuronal Calcium Sensor is a large family of proteins which work as calcium dependent molecular switches and includes members like Frequenin (NCS1), recoverin, GCAP, neurocalcin, visinin etc.[1] All the members carry 4 EF hand motifs (out of which only 2 or 3 bind calcium) and an N-myristoyl group.[2]

  1. ^ Burgoyne RD (2007). "Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling". Nat. Rev. Neurosci. 8 (3): 182–193. doi:10.1038/nrn2093. PMC 1887812. PMID 17311005.
  2. ^ Burgoyne RD, O'Callaghan DW, Hasdemir B, Haynes LP, Tepikin AV (2004). "Neuronal Ca2+-sensor proteins: multitalented regulators of neuronal function". Trends Neurosci. 27 (4): 203–9. doi:10.1016/j.tins.2004.01.010. PMID 15046879. S2CID 24156457.

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Neuronal calcium sensor

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Neuronal Calcium Sensor is a large family of proteins which work as calcium dependent molecular switches and includes members like Frequenin (NCS1), recoverin...

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Calcium signaling

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mediators of ICRAC. Calcium is a ubiquitous second messenger with wide-ranging physiological roles. These include muscle contraction, neuronal transmission (as...

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Freq

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the free dictionary. Freq may refer to: Frequency (abbreviation) Neuronal calcium sensor-1, protein also known as frequenin homolog or freq Freq (album)...

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Nerve tissue protein

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Protein 7B2 Neurofilament Proteins Neurogranin Neuronal Apoptosis-Inhibitory Protein Neuronal Calcium-Sensor Proteins Neuropeptides Olfactory Marker Protein...

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NCS1

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ncs1 or NCS1 may refer to: Neuronal calcium sensor Neuronal calcium sensor-1 Nucleobase Cation Symporter 1 National Comorbidity Survey This disambiguation...

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NCS

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complex syndrome Nerve conduction study, a medical diagnostic test Neuronal calcium sensor, a family of proteins Thiocyanate, an organic compound in the cyanate...

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PPP1R1B

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pathway is suggested to be involved on this regulation. Also, neuronal calcium sensor-1 was suggested to modulate the expression of DARPP-32. PPP1R1B...

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Inositol trisphosphate

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PMC 6671165. PMID 18171931. Bezprozvanny, I.; Hayden, M.R. (2004). "Deranged neuronal calcium signaling and Huntington disease". Biochemical and Biophysical Research...

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Hippocalcin

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encoded by the HPCA gene. Hippocalcin is a calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family of proteins. It is expressed...

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Neurocalcin

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Neurocalcin is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family of proteins. It expressed in mammalian brains...

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Dopamine receptor D2

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activity. In mice, regulation of D2R surface expression by the neuronal calcium sensor-1 (NCS-1) in the dentate gyrus is involved in exploration, synaptic...

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Recoverin

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Recoverin (abbreviated Recov) is a 23 kilodalton (kDa) neuronal calcium-binding protein that is primarily detected in the photoreceptor cells of the eye...

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Calmodulin

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unable to bind calcium themselves, and use calmodulin as a calcium sensor and signal transducer. Calmodulin can also make use of the calcium stores in the...

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Zinc

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Golovin, AV; Permyakov, SE; Zernii, EY (2018). "Functional Status of Neuronal Calcium Sensor-1 Is Modulated by Zinc Binding". Frontiers in Molecular Neuroscience...

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Calcium in biology

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mitochondrial matrix free calcium concentration rises to the tens of micromolar levels in situ during neuronal activity. The effects of calcium on human cells are...

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Calbindin

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calcium-binding domains, and 2 modified domains that have lost their calcium-binding capacity. Calbindin acts as a calcium buffer and calcium sensor and...

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Ryanodine receptor

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Ryanodine receptors (RyR for short) form a class of intracellular calcium channels in various forms of excitable animal tissue like muscles and neurons...

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Calcium imaging

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observe the activity of neuronal circuits during ongoing behavior. Chemical indicators are small molecules that can chelate calcium ions. All these molecules...

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Calretinin

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similar vitamin D-dependent calcium-binding protein, calbindin-28kDa. Calretinin has an important role as a modulator of neuronal excitability including the...

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BK channel

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increase in calcium levels. Structurally, BK channels are homologous to voltage- and ligand-gated potassium channels, having a voltage sensor and pore as...

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Troponin C

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complex. It contains four calcium-binding EF hands, although different isoforms may have fewer than four functional calcium-binding subdomains. It is...

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