dentate gyrus of hippocampal formation granule cell
otic placode
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
protein binding
phospholipid binding
Cellular component
actin cytoskeleton
cytoplasm
cell junction
synapse
synaptic vesicle membrane
cytoskeleton
membrane
cytoplasmic vesicle
synaptic vesicle
leading edge membrane
cytosol
plasma membrane
Biological process
endocytosis
chemical synaptic transmission
membrane organization
synaptic vesicle endocytosis
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
273
218038
Ensembl
ENSG00000078053
ENSMUSG00000021314
UniProt
P49418
Q7TQF7
RefSeq (mRNA)
NM_001635 NM_139316
NM_175007 NM_001289546
RefSeq (protein)
NP_001626 NP_647477
NP_001276475 NP_778172
Location (UCSC)
Chr 7: 38.38 – 38.63 Mb
Chr 13: 19.13 – 19.34 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Amphiphysin is a protein that in humans is encoded by the AMPH gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000078053 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000021314 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^De Camilli P, Thomas A, Cofiell R, Folli F, Lichte B, Piccolo G, Meinck HM, Austoni M, et al. (December 1993). "The synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen of Stiff-Man syndrome with breast cancer". The Journal of Experimental Medicine. 178 (6): 2219–23. doi:10.1084/jem.178.6.2219. PMC 2191289. PMID 8245793.
^"Entrez Gene: AMPH amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)".
Amphiphysin is a protein that in humans is encoded by the AMPH gene. This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles...
the BAR dimer. Amphiphysin, endophilin, BRAP1/bin2 and nadrin are examples of such proteins containing an N-BAR. The Drosophila amphiphysin N-BAR (DA-N-BAR)...
box-dependent-interacting protein 1, also known as Bridging Integrator-1 and Amphiphysin-2 is a protein that in humans is encoded by the BIN1 gene. This gene...
The main antibodies within this group are those against Hu, Ma2, CV2, amphiphysin and Ri. The syndrome of anti-Ma2 encephalitis may be clinically mistaken...
separate complexes in the nerve terminal. Interactions with endophilin and amphiphysin". J. Biol. Chem. 272 (43): 27239–45. doi:10.1074/jbc.272.43.27239. PMID 9341169...
are large protein complexes composed primarily of subunits of two Bin-Amphiphysin-RVS (BAR) domain containing proteins Pil1 and Lsp1. These two paralogue...
with the presence of antibodies against onconeural antigen, Hu, Yo, amphiphysin, or CV2/CRMP5, which recognize and bind to both tumor cells and peripheral...
the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites". The Journal...
humans is encoded by the SH3GLB1 gene. Endophilin-B1 belongs to the Bin/Amphiphysin/Rvs167 (BAR) family of proteins and plays a critical role in mitochondrial...
regulated by MITF. CDK5R1 has been shown to interact with: Actinin, alpha 1 Amphiphysin, Beta-catenin, CAMK2A, CDK5RAP2, Cyclin-dependent kinase 5, Protein SET...
clathrin-mediated endocytosis. More information is found on endocytosis.org. Amphiphysin Epsin Bao H, Daniels RW, MacLeod GT, Charlton MP, Atwood HL, Zhang B...
(1997). "Identification and characterization of a nerve terminal-enriched amphiphysin isoform". J. Biol. Chem. 272 (26): 16700–6. doi:10.1074/jbc.272.26.16700...
encoded by the SH3GL2 gene. SH3GL2 has been shown to interact with DNM1, Amphiphysin, ADAM9, SH3KBP1 and ADAM15. GRCh38: Ensembl release 89: ENSG00000107295...
pleckstrin homology (PH) domain, phosphotyrosine-binding (PTB) domain and Bin–Amphiphysin–Rvs (BAR) domain. APPL1 is an adaptor protein localized to a subset of...
surface to respond to environmental signals. She has explored how dynamin, amphiphysin and actin work together during the formation of cell membranes. Ayscough...
domain. The fold of the IMD domain closely resembles that of the BAR (Bin-Amphiphysin-RVS) domain, a functional module serving both as a sensor and inducer...
Kurosu H, Katada T (2004). "RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway". J. Cell Sci. 116 (Pt 20):...
vesicle endocytosis. Specifically, the c-terminal domain interacts with amphiphysin, endophilin, DAP160/intersectin, syndapin and Eps15. The function of...
Nathalie; De Gunzburg Jean; Camonis Jacques (May 2003). "Sorting nexin 4 and amphiphysin 2, a new partnership between endocytosis and intracellular trafficking"...
binding of the protein to endocytosis-related proteins such as ITSN1 and amphiphysin 1 and 2. This gene is located in the minimal candidate region for the...
Gertler FB, De Camilli P (Dec 2003). "Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin...
be a precursor for the development of familial Alzheimer's Disease. Amphiphysin AP180 Epsin Exomer Muniscins Pearse BM, Smith CJ, Owen DJ (April 2000)...
interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin". Journal of Neurochemistry. 84 (2): 253–65. doi:10.1046/j.1471-4159...