negative regulation of epidermal growth factor receptor signaling pathway
endocytosis
antigen processing and presentation of exogenous peptide antigen via MHC class II
central nervous system development
synaptic vesicle endocytosis
regulation of receptor internalization
signal transduction
membrane organization
synaptic vesicle uncoating
neuron projection development
dendrite extension
cellular response to brain-derived neurotrophic factor stimulus
lipid tube assembly
membrane tubulation
membrane bending
vesicle scission
positive regulation of membrane tubulation
regulation of clathrin-dependent endocytosis
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
6456
20404
Ensembl
ENSG00000107295
ENSMUSG00000028488
UniProt
Q99962
Q62420
RefSeq (mRNA)
NM_003026
NM_019535
RefSeq (protein)
NP_003017
NP_062408
Location (UCSC)
Chr 9: 17.58 – 17.8 Mb
Chr 4: 85.12 – 85.56 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000107295 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000028488 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Giachino C; Lantelme E; Lanzetti L; Saccone S; Bella Valle G; Migone N (Jul 1997). "A novel SH3-containing human gene family preferentially expressed in the central nervous system". Genomics. 41 (3): 427–34. doi:10.1006/geno.1997.4645. PMID 9169142.
Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene. SH3GL2 has been shown to interact with DNM1, Amphiphysin, ADAM9, SH3KBP1 and...
Chowdhury S, Roy B, Roychowdhury S, Panda CK. SNP rs1049430 in the 3'-UTR of SH3GL2 regulates its expression: Clinical and prognostic implications in head and...
DNM1 has been shown to interact with: AMPH, FNBP1, Grb2 NCK1, PACSIN1, and SH3GL2. GRCh38: Ensembl release 89: ENSG00000106976 – Ensembl, May 2017 GRCm38:...
interactions. ADAM15 has been shown to interact with: Grb2, HCK, Lck and SH3GL2, and SNX9. The alternatively spliced isoforms have also been shown to exhibit...