RAB5B information

RAB5B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HEI
Identifiers
Aliases	RAB5B, Rab-5B, member RAS oncogene family
External IDs	OMIM: 179514; MGI: 105938; HomoloGene: 104027; GeneCards: RAB5B; OMA:RAB5B - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	55,996,683 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	128,532,133 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; epithelium of colon; ; skin of leg; ; ectocervix; ; popliteal artery; ; tibial arteries; ; skin of abdomen; ; muscle layer of sigmoid colon; ; gastric mucosa; ; right coronary artery;
	Top expressed in
	granulocyte; ; dentate gyrus of hippocampal formation granule cell; ; muscle of thigh; ; lip; ; primary visual cortex; ; superior frontal gyrus; ; esophagus; ; neural layer of retina; ; genital tubercle; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GDP binding; GTP binding; GTP-dependent protein binding; protein binding; GTPase activity;
Cellular component	endosome; membrane; melanosome; endocytic vesicle; intracellular anatomical structure; early endosome; extracellular exosome; plasma membrane; secretory granule membrane; early endosome membrane; intracellular membrane-bounded organelle; anchored component of synaptic vesicle membrane;
Biological process	regulation of endocytosis; antigen processing and presentation; endosome organization; plasma membrane to endosome transport; protein transport; neutrophil degranulation; transport; intracellular protein transport; Rab protein signal transduction; endocytosis;
	Sources:Amigo / QuickGO
Orthologs
	5869
	19344
	ENSG00000111540
	ENSMUSG00000000711
	P61020
	P61021
	NM_001252036; NM_001252037; NM_002868
	NM_011229; NM_177411
	NP_001238965; NP_001238966; NP_002859
	NP_803130
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rab-5B is a protein that in humans is encoded by the RAB5B gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000111540 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000000711 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wilson DB, Wilson MP (Apr 1992). "Identification and subcellular localization of human rab5b, a new member of the ras-related superfamily of GTPases". J Clin Invest. 89 (3): 996–1005. doi:10.1172/JCI115683. PMC 442949. PMID 1541686.
^ Chiariello M, Bruni CB, Bucci C (Aug 1999). "The small GTPases Rab5a, Rab5b and Rab5c are differentially phosphorylated in vitro". FEBS Lett. 453 (1–2): 20–4. doi:10.1016/S0014-5793(99)00686-9. PMID 10403367. S2CID 30308802.
^ "Entrez Gene: RAB5B RAB5B, member RAS oncogene family".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000111540 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000000711 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1541686-5] Wilson DB, Wilson MP (Apr 1992). "Identification and subcellular localization of human rab5b, a new member of the ras-related superfamily of GTPases". J Clin Invest. 89 (3): 996–1005. doi:10.1172/JCI115683. PMC 442949. PMID 1541686.

[pmid10403367-6] Chiariello M, Bruni CB, Bucci C (Aug 1999). "The small GTPases Rab5a, Rab5b and Rab5c are differentially phosphorylated in vitro". FEBS Lett. 453 (1–2): 20–4. doi:10.1016/S0014-5793(99)00686-9. PMID 10403367. S2CID 30308802.

[entrez-7] "Entrez Gene: RAB5B RAB5B, member RAS oncogene family".

RAB5B information

and 5 Related for: RAB5B information

RAB5B

Ras superfamily

Housekeeping gene

RAB5A

Rabaptin