Adenosine A2A receptor antagonists are a class of drugs that blocks adenosine at the adenosine A2A receptor. Notable adenosine A2A receptor antagonists include caffeine, theophylline and istradefylline.[1]
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four known types of adenosinereceptors in humans: A1, A2A, A2B and A3; each is encoded by a different gene. The adenosinereceptors are commonly known...
Cellular signaling by adenosine occurs through four known adenosinereceptor subtypes (A1, A2A, A2B, and A3). Extracellular adenosine concentrations from...
The adenosine A1 receptor (A1AR) is one member of the adenosinereceptor group of G protein-coupled receptors with adenosine as endogenous ligand. A1 receptors...
include: D1–D2 dopamine receptor heteromer D2–adenosineA2A D2–ghrelin receptor D2sh–TAAR1 The D2 receptor has been shown to form hetorodimers in vitro...
The adenosine A2B receptor, also known as ADORA2B, is a G-protein coupled adenosinereceptor, and also denotes the human adenosine A2b receptor gene which...
The adenosine A3 receptor, also known as ADORA3, is an adenosinereceptor, but also denotes the human gene encoding it. Adenosine A3 receptors are G protein-coupled...
Purification of the receptor further verified its existence. The first attempt to purify the receptor involved the use of a novel opioid antagonist called chlornaltrexamine...
several potent, highly selective, orally bioavailable oxytocin antagonists. Oxytocin receptor agonists have also been developed. Peptide Carbetocin Demoxytocin...
Caffeine is an antagonist of adenosineA2Areceptors, and knockout mouse studies have specifically implicated antagonism of the A2Areceptor as responsible...
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline)...
melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a...
and scopolamine) manipulate these two distinct receptors by acting as selective agonists or antagonists. Acetylcholine (ACh) is a neurotransmitter found...
selective A1 and A2Aadenosine agonists found theacrine pretreatment attenuated the expected motor depression induced by adenosine agonism, indicating...
2006). "Inhibition of monoamine oxidase B by analogues of the adenosineA2Areceptorantagonist (E)-8-(3-chlorostyryl)caffeine (CSC)". Bioorg. Med. Chem....
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