Chemical compound
Acebutolol Trade names Sectral, Prent, others AHFS/Drugs.com Monograph MedlinePlus a687003 License data
Pregnancy category Routes of administration By mouth, IV ATC code Legal status
UK : POM (Prescription only)
In general: ℞ (Prescription only)
Bioavailability 40% (range 35 to 50%) Metabolism Hepatic Elimination half-life 3-4 hours (parent drug) 8-13 hours (active metabolite) Excretion Renal: 30% Biliary: 60%
(RS )-N -{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}butanamide
CAS Number 37517-30-9 Y PubChem CID IUPHAR/BPS DrugBank DB01193 Y ChemSpider 1901 Y UNII KEGG D02338 Y ChEBI CHEBI:2379 Y ChEMBL ChEMBL642 Y CompTox Dashboard (EPA ) DTXSID2048539 ECHA InfoCard 100.048.654 Formula C 18 H 28 N 2 O 4 Molar mass 336.432 g·mol−1 3D model (JSmol) Melting point 121 °C (250 °F)
O=C(Nc1ccc(OCC(O)CNC(C)C)c(c1)C(=O)C)CCC
InChI=1S/C18H28N2O4/c1-5-6-18(23)20-14-7-8-17(16(9-14)13(4)21)24-11-15(22)10-19-12(2)3/h7-9,12,15,19,22H,5-6,10-11H2,1-4H3,(H,20,23)
Y Key:GOEMGAFJFRBGGG-UHFFFAOYSA-N
Y
(verify)
Acebutolol ,[1] sold under the brand names Sectral among others, is a beta blocker for the treatment of hypertension and arrhythmias. Acebutolol is a cardioselective beta-1 blocker and has intrinsic sympathetic activity. It is commonly used in the treatment of angina.
It was patented in 1967 and approved for medical use in 1973.[2]
^ Elks J, Ganellin CR (1990). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies . Springer. pp. 2–. ISBN 978-1-4757-2085-3 .
^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery . John Wiley & Sons. p. 461. ISBN 9783527607495 .
Last Update: 2023-12-24T14:07:31Z
Acebutolol , sold under the brand names Sectral among others, is a beta blocker for the treatment of hypertension and arrhythmias. Acebutolol is a cardioselective...
Word Count : 695
Last Update: 2024-05-09T09:37:51Z
Some beta blockers (e.g. oxprenolol, pindolol, penbutolol, labetalol and acebutolol ) exhibit intrinsic sympathomimetic activity (ISA). These agents are capable...
Word Count : 7108
Last Update: 2017-01-27T19:35:01Z
Carazolol C07AB01 Practolol C07AB02 Metoprolol C07AB03 Atenolol C07AB04 Acebutolol C07AB05 Betaxolol C07AB06 Bevantolol C07AB07 Bisoprolol C07AB08 Celiprolol...
Word Count : 404
Last Update: 2023-01-29T10:26:56Z
Diacetolol is the primary metabolite of acebutolol . It is a beta blocker and anti-arrhythmic agent. Basil B, Jordan R (May 1982). "Pharmacological properties...
Word Count : 55
Last Update: 2021-04-21T22:06:25Z
alcohols that are derivatives of 1-amino-2-propanol. Propanolamines include: Acebutolol Atenolol Betaxolol Bisoprolol Metoprolol Nadolol Penbutolol Phenylpropanolamine...
Word Count : 89
Last Update: 2024-04-02T05:19:08Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 6534
Last Update: 2023-10-26T06:41:58Z
Fimasartan Irbesartan Losartan Olmesartan Telmisartan Valsartan Beta blocker Acebutolol Atenolol Betaxolol Bisoprolol Carteolol Carvedilol Esmolol Labetalol Metoprolol...
Word Count : 340
Last Update: 2024-03-25T20:48:25Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 3769
Last Update: 2024-05-09T18:09:52Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 2336
Last Update: 2024-04-22T22:13:54Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 1413
Last Update: 2024-05-14T06:10:24Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 8668
Last Update: 2024-05-20T00:33:57Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 6615
Last Update: 2024-03-28T19:23:24Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 8663
Last Update: 2024-04-12T20:48:18Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 5498
Last Update: 2024-05-08T15:18:49Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 4889
Last Update: 2024-04-26T06:08:05Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 1690
Last Update: 2023-12-19T21:21:39Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 1748
Last Update: 2024-05-19T16:29:08Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 12537
Last Update: 2024-05-22T21:18:09Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 5377
Last Update: 2024-05-13T05:57:32Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 3886
Last Update: 2024-05-15T19:19:35Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 16528
Last Update: 2024-05-19T03:03:35Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 2535
Last Update: 2024-05-14T05:55:19Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 1266
Last Update: 2024-05-16T00:48:48Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 2681
Last Update: 2024-03-06T11:28:49Z
symptoms of hypoglycemia. Agents include either cardioselectives such as acebutolol or metoprolol, or non-cardioselectives such as oxprenolol or sotalol....
Word Count : 1035
Last Update: 2024-04-15T06:14:20Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 1174
Last Update: 2024-02-04T06:11:20Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 972
Last Update: 2024-02-28T05:46:20Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 927
Last Update: 2024-05-12T17:21:37Z
Vibegron Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonists Acebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoxime Amosulalol Ancarolol...
Word Count : 2102