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Von Willebrand factor type C domain information


von Willebrand factor type C domain
Identifiers
SymbolVWC
PfamPF00093
InterProIPR001007
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Von Willebrand factor, type C (VWFC or VWC)is a protein domain is found in various blood plasma proteins: complement factors B, C2, CR3 and CR4; the integrins (I-domains); collagen types VI, VII, XII and XIV; and other extracellular proteins.[1][2][3]

  1. ^ Colombatti A, Bonaldo P, Doliana R (1993). "Type A modules: interacting domains found in several non-fibrillar collagens and in other extracellular matrix proteins". Matrix. 13 (4): 297–306. doi:10.1016/S0934-8832(11)80025-9. PMID 8412987.
  2. ^ Smith KF, Haris PI, Chapman D, Perkins SJ, Williams SC, Sim RB (1994). "The secondary structure of the von Willebrand factor type A domain in factor B of human complement by Fourier transform infrared spectroscopy. Its occurrence in collagen types VI, VII, XII and XIV, the integrins and other proteins by averaged structure predictions". J. Mol. Biol. 238 (1): 104–119. doi:10.1006/jmbi.1994.1271. PMID 8145250.
  3. ^ Bork P (1991). "Shuffled domains in extracellular proteins". FEBS Lett. 286 (1): 47–54. doi:10.1016/0014-5793(91)80937-X. PMID 1864378. S2CID 22126481.

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Von Willebrand factor

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specific domains with a specific function; elements of note are: the D'/D3 domain, which binds to factor VIII (von Willebrand factor type D domain). the...

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Von Willebrand factor type C domain

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Von Willebrand factor, type C (VWFC or VWC)is a protein domain is found in various blood plasma proteins: complement factors B, C2, CR3 and CR4; the integrins...

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Von Willebrand factor type D domain

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Von Willebrand factor type D domain (vWD) is an evolutionarily-conserved protein domain found in, among others, the von Willebrand factor (vWF). vWF is...

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Von Willebrand factor type A domain

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The von Willebrand factor type A (vWA) domain is a protein domain named after its occurrence in von Willebrand factor (vWF), a large multimeric glycoprotein...

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Von willebrand factor a domain containing 7

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Von Willebrand factor A domain containing 7 is a protein that in humans is encoded by the VWA7 gene. See articles on Von Willebrand factor and on Von...

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ADAMTS13

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type 1 motif, member 13)—also known as von Willebrand factor-cleaving protease (VWFCP)—is a zinc-containing metalloprotease enzyme that cleaves von Willebrand...

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Chordin

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These repeats are homologous with domains in a number of extracellular matrix proteins, including von Willebrand factor. There are five named isoforms of...

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VWFC

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VWFC may refer to: Von Willebrand factor type C domain, a protein domain and family Very Wide Field Camera, space camera developed by NASA for Spacelab...

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Coagulation

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glycoprotein IIb/IIIa) to extracellular matrix proteins (e.g. von Willebrand factor) on cell membranes of damaged endothelial cells and exposed collagen...

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FSTL1

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cysteine residues), a Kazal-type serine protease inhibitor domain, 2 EF hand domains, and a Von Willebrand factor type C domain. FSTL1 has a role in development...

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LCCL domain

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with complement B-type domains, C-type lectin domains, von Willebrand type A domains, CUB domains, discoidin lectin domains or CAP domains. It has been proposed...

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Tumor necrosis factor receptor 1

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schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor". Bipolar Disord. 11 (7): 726–34. doi:10.1111/j.1399-5618...

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Vitellogenin

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lipovitellin-1, phosvitin, lipovitellin-2, von Willebrand factor type D domain (YGP40). This particular domain represents a conserved region found in several...

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CTGF

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cysteine-rich domains. These domains are, from N- to C-termini, the insulin-like growth factor binding protein (IGFBP) domain, the von Willebrand type C repeats...

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Platelet membrane glycoprotein

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collagen type I and IV. It consists of two subunits (α2 and β1). The α2 subunit includes a domain homologous to von Willebrand factor domain binding to...

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Caenorhabditis elegans

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300 bp to the sequence. The C. elegans Genome Project's Wilson et al. 1994 found CelVav and a von Willebrand factor A domain and with Wilson et al. 1998...

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CCN protein

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domains, which include the insulin-like growth factor-binding domain (IGFBP), the Von Willebrand factor type C domain (VWC), the thrombospondin type 1...

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Caplacizumab

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conjunction with plasma exchange and immunosuppression". It is an anti-von Willebrand factor humanized immunoglobulin. It acts by blocking platelet aggregation...

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Osteoprotegerin

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ligands include syndecan-1, glycosaminoglycans, von Willebrand factor, and factor VIII-von Willebrand factor complex. OPG has been identified as having a...

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Plasmin

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inflammation. It cleaves fibrin, fibronectin, thrombospondin, laminin, and von Willebrand factor. Plasmin, like trypsin, belongs to the family of serine proteases...

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Furin

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of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site". Proceedings of the...

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GP1BA

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linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association...

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