Von Willebrand factor type D domain (vWD) is an evolutionarily-conserved protein domain found in, among others, the von Willebrand factor (vWF). vWF is a large multimeric glycoprotein and it is synthesized by a type of bone marrow cell called megakaryocytes. The vWD domain allows vWF to perform its blood-clotting function by carrying factor VIII around.
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VonWillebrandfactor, type C (VWFC or VWC)is a protein domain is found in various blood plasma proteins: complement factors B, C2, CR3 and CR4; the integrins...
The vonWillebrandfactortype A (vWA) domain is a protein domain named after its occurrence in vonWillebrandfactor (vWF), a large multimeric glycoprotein...
lipovitellin-1, phosvitin, lipovitellin-2, vonWillebrandfactortypeDdomain (YGP40). This particular domain represents a conserved region found in several...
type 1 motif, member 13)—also known as vonWillebrandfactor-cleaving protease (VWFCP)—is a zinc-containing metalloprotease enzyme that cleaves von Willebrand...
glycoprotein IIb/IIIa) to extracellular matrix proteins (e.g. vonWillebrandfactor) on cell membranes of damaged endothelial cells and exposed collagen...
with complement B-typedomains, C-type lectin domains, vonWillebrandtype A domains, CUB domains, discoidin lectin domains or CAP domains. It has been proposed...
cysteine-rich domains. These domains are, from N- to C-termini, the insulin-like growth factor binding protein (IGFBP) domain, the vonWillebrandtype C repeats...
collagen type I and IV. It consists of two subunits (α2 and β1). The α2 subunit includes a domain homologous to vonWillebrandfactordomain binding to...
conjunction with plasma exchange and immunosuppression". It is an anti-vonWillebrandfactor humanized immunoglobulin. It acts by blocking platelet aggregation...
ligands include syndecan-1, glycosaminoglycans, vonWillebrandfactor, and factor VIII-vonWillebrandfactor complex. OPG has been identified as having a...
inflammation. It cleaves fibrin, fibronectin, thrombospondin, laminin, and vonWillebrandfactor. Plasmin, like trypsin, belongs to the family of serine proteases...
Yoshioka A, Diaz J, Meyer D (October 1990). "Ristocetin and botrocetin involve two distinct domains of vonWillebrandfactor for binding to platelet membrane...
domains of this protein structure. The honey bees, the domain of unknown function 1943 (DUF1943), and the vonWillebrandfactor (vWF) typeDdomain were...
cysteine residues), a Kazal-type serine protease inhibitor domain, 2 EF hand domains, and a VonWillebrandfactortype C domain. FSTL1 has a role in development...
procollagen aminopeptidase, aggrecanase, and ADAMTS13 which cleaves vonWillebrandfactor. Unlike with MMPs, TIMPs are more selective in their ability to...
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