Transferrin receptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is encoded by the TFRC gene.[5][6] TfR1 is required for iron import from transferrin into cells by endocytosis.[7][8]
^ abcGRCh38: Ensembl release 89: ENSG00000072274 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000022797 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Sutherland R, Delia D, Schneider C, Newman R, Kemshead J, Greaves M (July 1981). "Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin". Proceedings of the National Academy of Sciences of the United States of America. 78 (7): 4515–9. Bibcode:1981PNAS...78.4515S. doi:10.1073/pnas.78.7.4515. PMC 319822. PMID 6270680.
^Rabin M, McClelland A, Kühn L, Ruddle FH (November 1985). "Regional localization of the human transferrin receptor gene to 3q26.2----qter". American Journal of Human Genetics. 37 (6): 1112–6. PMC 1684729. PMID 3002171.
^Aisen P (November 2004). "Transferrin receptor 1". The International Journal of Biochemistry & Cell Biology. 36 (11): 2137–43. doi:10.1016/j.biocel.2004.02.007. PMID 15313461.
^Moos T (November 2002). "Brain iron homeostasis". Danish Medical Bulletin. 49 (4): 279–301. PMID 12553165.
and 22 Related for: Transferrin receptor 1 information
Transferrinreceptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is encoded by the TFRC gene. TfR1...
Transferrinreceptor (TfR) is a carrier protein for transferrin. It is needed for the import of iron into cells and is regulated in response to intracellular...
transferrin receptors found in humans denoted as transferrinreceptor1 (TfR1) and transferrinreceptor 2 (TfR2). Although both are similar in structure...
transferrinreceptor conventionally refers to the cleaved extracellular portion of transferrinreceptor1 that is released into serum. This receptor is...
take up iron primarily through receptor-mediated endocytosis via transferrinreceptor1 (TFR1), transferrinreceptor 2 (TFR2) and GAPDH. TFR1 has a 30-fold...
Sabia in addition to the non pathogenic Amapari virus, use the transferrinreceptor1. A small aliphatic amino acid at the GP1 glycoprotein amino acid...
a type of iron overload disorder associated with deficiencies in transferrinreceptor 2. It exhibits an autosomal recessive inheritance pattern. The first...
potential target to attenuate immune rejection. Antibodies CD71/Transferrinreceptor-1 CD13 marker for kidney disorder CD33 marker for AML treatment CD4+/CD8+...
co-develop/commercialize at least one of CytomX Probody's conjugates against CD71 (transferrinreceptor1). In March 2020, AbbVie announced plans to evaluate the Kaletra/Aluvia...
(vesicles up to 1 μm in diameter with connected tubules of approx. 50 nm diameter). Markers include RAB5A and RAB4, Transferrin and its receptor and EEA1. Late...
take up iron primarily through receptor-mediated endocytosis via transferrinreceptor1 (TFR1), transferrinreceptor 2 (TFR2) and GAPDH. TFR1 has a 30-fold...
hemochromatosis: transferrinreceptor-1, ferroportin, ceruloplasmin, ferritin light and heavy chains, iron regulatory proteins (IRP)-1 and -2, and hepcidin"...
active against all tested mammarenaviruses that use the transferrinreceptor1 as their receptor was under investigation in 2020. Radoshitzky, SR; Buchmeier...
ferroportin. Ferroportin Q248H also unregulated the expression of transferrinreceptor-1 in the same way as wild type. This indicates the ferroportin Q248H...
the BBB via transport on brain endothelial receptors such as the insulin receptor or transferrinreceptor. The transporter protein acts as a molecular...
that have different receptors responsible for the receptor-mediated endocytosis of ligands, e.g. low density lipoprotein, transferrin, growth factors, antibodies...
Punnonen, K; Rajamäki, A; Irjala, K (October 1998). "Serum transferrinreceptor and transferrinreceptor-ferritin index identify healthy subjects with subclinical...
known as lactotransferrin (LTF), is a multifunctional protein of the transferrin family. Lactoferrin is a globular glycoprotein with a molecular mass...
transcripts that encode iron metabolism genes, including ferritin, transferrinreceptor1, ferroportin, HIF2 alpha, and several other transcripts. IRP1 acquires...
Chaturvedi, MM; Aggarwal, BB (2007). "Gambogic acid, a novel ligand for transferrinreceptor, potentiates TNF-induced apoptosis through modulation of the nuclear...
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