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Arenavirus information


Arenaviridae
(A) Electron micrograph of Lassa virus, bar = 100nm (B) diagram and (C) genome of arenavirus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Arenaviridae
Genera
  • Antennavirus
  • Hartmanivirus
  • Innmovirus
  • Mammarenavirus
  • Reptarenavirus

An arenavirus is a bi- or trisegmented ambisense RNA virus that is a member of the family Arenaviridae.[1][2] These viruses infect rodents and occasionally humans. A class of novel, highly divergent arenaviruses, properly known as reptarenaviruses, have also been discovered which infect snakes to produce inclusion body disease, mostly in boa constrictors. At least eight arenaviruses are known to cause human disease. The diseases derived from arenaviruses range in severity. Aseptic meningitis, a severe human disease that causes inflammation covering the brain and spinal cord, can arise from the lymphocytic choriomeningitis virus. Hemorrhagic fever syndromes, including Lassa fever, are derived from infections such as Guanarito virus, Junin virus, Lassa virus, Lujo virus,[3] Machupo virus, Sabia virus, or Whitewater Arroyo virus.[4] Because of the epidemiological association with rodents, some arenaviruses and bunyaviruses are designated as roboviruses.

  1. ^ Radoshitzky, SR; Buchmeier, MJ; Charrel, RN; Clegg, JCS; Gonzalez, JJ; Günther, S; Hepojoki, J; Kuhn, JH; Lukashevich, IS; Romanowski, V; Salvato, MS; Sironi, M; Stenglein, MD; de la Torre, JC; ICTV Report, Consortium (August 2019). "ICTV Virus Taxonomy Profile: Arenaviridae". The Journal of General Virology. 100 (8): 1200–1201. doi:10.1099/jgv.0.001280. PMID 31192784.
  2. ^ Shi, Mang; Lin, Xian-Dan; Chen, Xiao; Tian, Jun-Hua; Chen, Liang-Jun; Li, Kun; Wang, Wen; Eden, John-Sebastian; Shen, Jin-Jin; Li, Liu; Holmes, Edward C.; Zhang, Yong-Zhen (2018). "The evolutionary history of vertebrate RNA viruses". Nature. 561 (7722): 202. doi:10.1038/s41586-018-0310-0. PMID 29946168. S2CID 49433735.
  3. ^ Briese T, Paweska JT, McMullan LK, et al. (May 2009). "Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa". PLOS Pathog. 5 (5): e1000455. doi:10.1371/journal.ppat.1000455. PMC 2680969. PMID 19478873.
  4. ^ Botten, J; Whitton, JL; Barrowman, P; Sidney, J; Whitmire, JK; Alexander, J; Kotturi, MF; Sette, A; Buchmeier, MJ (2010). "A Multivalent Vaccination Strategy for the Prevention of Old World Arenavirus Infection in Humans". Journal of Virology. 84 (19): 9947–56. doi:10.1128/JVI.00672-10. PMC 2937778. PMID 20668086.

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Arenavirus

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An arenavirus is a bi- or trisegmented ambisense RNA virus that is a member of the family Arenaviridae. These viruses infect rodents and occasionally humans...

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Notifiable diseases in the United States

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virus New World arenavirus – Guanarito virus New World arenavirus – Junin virus New World arenavirus – Machupo virus New World arenavirus – Sabia virus...

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Lujo mammarenavirus

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Johannesburg (Republic of South Africa). It is the second pathogenic Arenavirus to be described from the African continent—the first being Lassa virus—and...

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Chapare mammarenavirus

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a medical intern and a gastroenterologist. Like other members of the Arenavirus family, the specific zoonotic reservoir and primary transmission vector...

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Inclusion body disease

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as the causative agent of IBD, but identification of highly divergent arenavirus sequences from boa constrictors with IBD suggested arenaviruses to be...

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Viral hemorrhagic fever

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prophylactic (preventive) ribavirin may be effective for some bunyavirus and arenavirus infections. VHF isolation guidelines dictate that all VHF patients (with...

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Lassa mammarenavirus

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Lassa mammarenavirus (LASV) is an arenavirus that causes Lassa hemorrhagic fever, a type of viral hemorrhagic fever (VHF), in humans and other primates...

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List of infections of the central nervous system

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Japanese encephalitis La Crosse encephalitis Lymphocytic choriomeningitis by Arenavirus Measles encephalitis Mumps Nipah virus encephalitis Poliomyelitis Progressive...

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Encephalitis

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Louis encephalitis, West Nile virus), bunyavirus (La Crosse strain), arenavirus (lymphocytic choriomeningitis virus), reovirus (Colorado tick virus),...

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Antiviral drug

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infectious viruses, including dengue flavivirus, Amapari and Tacaribe arenavirus, Guama bunyavirus, H1N1 influenza and rhinovirus, and was additionally...

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Argentinian mammarenavirus

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mammarenavirus, better known as the Junin virus or Junín virus (JUNV), is an arenavirus in the Mammarenavirus genus that causes Argentine hemorrhagic fever (AHF)...

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Lymphocytic choriomeningitis

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membrane, releasing the virion out from the infected cell. The first arenavirus, Lymphocytic choriomeningitis mammarenavirus (LCMV), was isolated in 1933...

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Mammarenavirus

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of mammal and the former name Arenavirus, and differentiates it from the reptile-associated Reptarenavirus. Arenavirus comes from the Latin arena (sand)...

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Whitewater Arroyo mammarenavirus

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Whitewater Arroyo mammarenavirus (WWAV) is a zoonotic Arenavirus associated with hemorrhagic fever with liver failure. WWAV is an emerging virus; previously...

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Morogoro virus

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Morogoro virus is an East African arenavirus infecting the multimammate mouse (Mastomys natalensis). The virus is genetically closely related to Lassa...

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List of notifiable diseases

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Ebola virus Viral hemorrhagic fever Viral hemorrhagic fever, including Arenavirus (new world), Crimean-Congo hemorrhagic fever, Dengue hemorraghic fever...

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Brazilian hemorrhagic fever

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(BzHF) is an infectious disease caused by Brazilian mammarenavirus, an arenavirus. Brazilian mammarenavirus is one of the arenaviruses from South America...

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Lassa fever

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negative-sense, single-stranded RNA viruses. Specifically it is an old world arenavirus, which is enveloped, single-stranded, and bi-segmented RNA. Lassa virus...

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Bolivian hemorrhagic fever

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http://www.cfsph.iastate.edu/Factsheets/pdfs/viral_hemorrhagic_fever_arenavirus.pdf, last updated: February 23, 2010. Aguilar PV, Carmago W, Vargas J...

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Lunk

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fool or idiot, a mindless golem. Lunk can also refer to: In reality An arenavirus (LNKV). Lunk, a nickname for Steve Lundquist an Olympic swimmer A lunk...

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Venezuelan hemorrhagic fever

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possible, but uncommon. VHF has many similarities to Lassa fever and to the arenavirus hemorrhagic fevers that occur in Argentina and Bolivia. It causes fever...

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DRACO

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infectious viruses, including dengue flavivirus, Amapari and Tacaribe arenavirus, Guama bunyavirus, H1N1 influenza and rhinovirus, and was additionally...

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Argentine hemorrhagic fever

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infectious disease occurring in Argentina. It is caused by the Junín virus (an arenavirus, closely related to the Machupo virus, causative agent of Bolivian hemorrhagic...

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SIGA Technologies

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antiviral drug for treating and preventing Lassa fever and others of arenavirus origin. That year, it sealed a contract worth over $400 million to sell...

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Emerging infectious disease

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category A) Chapare virus (category A areanavirus) Lujo (category A arenavirus) Chlamydia psittaci (category B) Naegleria fowleri (category B) Balamuthia...

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Bear Canyon mammarenavirus

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J. P.; Cajimat, M. N.; Bradley, R. D. (2002). "Bear Canyon Virus: An Arenavirus Naturally Associated with the California Mouse (Peromyscus californicus)"...

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Lassa

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(Pavonia hastata), a shrub in the family Malvaceae Lassa virus (LASV), the arenavirus that causes Lassa hemorrhagic fever, named after Lassa in Borno State...

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Mopeia mammarenavirus

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East African country of Mozambique in 1977. It is of the "Old World" Arenavirus lineage and is closely related to Lassa mammarenavirus, sharing 75% of...

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Bat virome

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associated with rodents, though some can cause illness in humans. The first arenavirus identified in bats was Tacaribe mammarenavirus, which was isolated from...

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