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Tetrandrine
Names
IUPAC name
9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6 .18,12 .114,18 .027,31 .022,33 ]hexatriaconta-3,5,8(34),9,11,18,20,22(33),24(32),25,27(31),35-dodecaene
Identifiers
CAS Number
518-34-3 Y
3D model (JSmol)
ChEMBL
ChEMBL176045 N
ECHA InfoCard
100.208.615
KEGG
C09654 Y
UNII
29EX23D5AJ N
DTXSID10178062
CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
Properties
Chemical formula
C38 H42 N2 O6
Molar mass
622.74988
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Tetrandrine , a bis-benzylisoquinoline alkaloid, is a calcium channel blocker.[1] It is isolated from the plant Stephania tetrandra ,[2] and other Chinese and Japanese herbs.
^ Bhagya, N; Chandrashekar, KR (1 May 2016). "Tetrandrine – A molecule of wide bioactivity". Phytochemistry . 125 : 5–13. Bibcode:2016PChem.125....5B. doi:10.1016/j.phytochem.2016.02.005. ISSN 0031-9422. PMID 26899361. Retrieved 24 February 2022 .
^ Zhang, Lijin; Geng, Yanling; Duan, Wenjuan; Wang, Daijie; Fu, Maorun; Wang, Xiao (2009). "Ionic liquid-based ultrasound-assisted extraction of fangchinoline and tetrandrine from Stephaniae tetrandrae". Journal of Separation Science . 32 (20): 3550–3554. doi:10.1002/jssc.200900413. PMID 19764054.
Last Update: 2023-12-20T19:21:56Z
Tetrandrine , a bis-benzylisoquinoline alkaloid, is a calcium channel blocker. It is isolated from the plant Stephania tetrandra, and other Chinese and...
Word Count : 761
Last Update: 2024-02-17T21:35:06Z
acrid, bitter and cold. The part used is the root. Stephania contains tetrandrine , a potent smooth muscle relaxant. Stephania alkaloids have curare-like...
Word Count : 786
Last Update: 2024-06-15T16:22:11Z
Prenylamine Rhynchophylline Sesamodil Silperisone Sipatrigine Terodiline Tetrandrine Tolperisone Trimethadione Valperinol Activators L-type-selective: Bay...
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Prenylamine Rhynchophylline Sesamodil Silperisone Sipatrigine Terodiline Tetrandrine Tolperisone Trimethadione Valperinol Activators L-type-selective: Bay...
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Prenylamine Rhynchophylline Sesamodil Silperisone Sipatrigine Terodiline Tetrandrine Tolperisone Trimethadione Valperinol Activators L-type-selective: Bay...
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Prenylamine Rhynchophylline Sesamodil Silperisone Sipatrigine Terodiline Tetrandrine Tolperisone Trimethadione Valperinol Activators L-type-selective: Bay...
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Prenylamine Rhynchophylline Sesamodil Silperisone Sipatrigine Terodiline Tetrandrine Tolperisone Trimethadione Valperinol Activators L-type-selective: Bay...
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includes aconite, ginseng, gossypol, gynura, licorice, lily of the valley, tetrandrine , and yohimbine. Aconite can cause abnormally slow heart rates and abnormal...
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