Solifenacin, sold as the brand name Vesicare[a] among others, is a medicine used to treat overactive bladder and neurogenic detrusor overactivity (NDO).[1][2] It may help with incontinence, urinary frequency, and urinary urgency.[3]
Benefits appear similar to other medications in the class.[4] It is taken by mouth.[1]
Common side effects include dry mouth, constipation, and urinary tract infection.[1][2] Severe side effects may include urinary retention, QT prolongation, hallucinations, glaucoma, and anaphylaxis.[1][3][2] It is unclear if use is safe during pregnancy.[1] It is of the antimuscarinic class and works by decreasing bladder contractions.[1]
Solifenacin was approved for medical use in the United States in 2004.[1][2][5] In 2021, it was the 228th most commonly prescribed medication in the United States, with more than 1million prescriptions.[6][7]
Cite error: There are <ref group=lower-alpha> tags or {{efn}} templates on this page, but the references will not show without a {{reflist|group=lower-alpha}} template or {{notelist}} template (see the help page).
^ abcdefg"Solifenacin Succinate Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists.
^ abcd"FDA Approves First Treatment for a Form of Bladder Dysfunction in Pediatric Patients as Young as 2 Years of Age". U.S. Food and Drug Administration (FDA) (Press release). 26 May 2020. Retrieved 26 May 2020. This article incorporates text from this source, which is in the public domain.
^ abBritish national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 761. ISBN 9780857113382.
^"[93] Are claims for newer drugs for overactive bladder warranted?". Therapeutics Initiative. 22 April 2015. Retrieved 17 March 2019.
^Cite error: The named reference FDA approval was invoked but never defined (see the help page).
^"The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
^"Solifenacin - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
Solifenacin, sold as the brand name Vesicare among others, is a medicine used to treat overactive bladder and neurogenic detrusor overactivity (NDO)....
bladder. Its benefits are similar to antimuscarinic medication such as solifenacin or tolterodine. It is taken by mouth. Common side effects include high...
long periods of time. It works similar to tolterodine, darifenacin, and solifenacin, although it is usually preferred over these medications. It is sometimes...
cross the blood–brain barrier. Oxybutynin, tolterodine, darifenacin, and solifenacin are tertiary amines while trospium chloride and propantheline are quaternary...
mass: 362.465 g/mol, exact mass: 362.1994 u) may refer to: Dexetimide Solifenacin This set index page lists chemical structure articles associated with...
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This article incorporates text from this source, which is in the public domain.
