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CD68 information


CD68
Identifiers
AliasesCD68, GP110, LAMP4, SCARD1, CD68 molecule
External IDsOMIM: 153634 MGI: 88342 HomoloGene: 955 GeneCards: CD68
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001251
NM_001040059

NM_001291058
NM_009853

RefSeq (protein)

NP_001035148
NP_001242

NP_001277987

Location (UCSC)Chr 17: 7.58 – 7.58 MbChr 11: 69.56 – 69.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
CD68 immunostaining demonstrating macrophages and giant cells in a case of xanthogranulomatous pyelonephritis

CD68 (Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia).[5]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000129226 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000018774 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Holness CL, Simmons DL (March 1993). "Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins". Blood. 81 (6): 1607–13. doi:10.1182/blood.V81.6.1607.1607. PMID 7680921.

and 20 Related for: CD68 information

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CD68

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CD68 (Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating...

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Multiple sclerosis

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cerebro-spinal sclerosis, disseminated sclerosis, encephalomyelitis disseminata CD68-stained tissue shows several macrophages in the area of a demyelinated lesion...

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Histiocyte

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lysosomes – in relation to their specialised phagocytic function. They express CD68. Dendritic cells have an indented (bean-shaped) nucleus and cytoplasm with...

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Demyelinating disease

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Photomicrograph of a demyelinating MS-lesion: Immunohistochemical staining for CD68 highlights numerous macrophages (brown). Original magnification 10×. Specialty...

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Macrophage

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CD40, CD11b, CD64, F4/80 (mice)/EMR1 (human), lysozyme M, MAC-1/MAC-3 and CD68. Macrophages were first discovered and named by Élie Metchnikoff, a Russian...

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Cluster of differentiation

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CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85...

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Giant cell

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CD68 immunostaining demonstrating giant cells and macrophages...

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Lupus

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phagocytic cells in the germinal centers of secondary lymph nodes – express CD68 protein. These cells normally engulf B cells that have undergone apoptosis...

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Villonodular synovitis

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very different names, they have the same histology, and stain positive for CD68, HAM56, and vimentin. They are sometimes discussed together. O'Connell JX...

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Kell antigen system

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CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85...

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Carcinoembryonic antigen

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CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85...

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Programmed cell death protein 1

Last Update:

CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85...

Word Count : 5010

CD19

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CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85...

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Pyelonephritis

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Pyelonephritis Other names Kidney infection CD68 immunostaining on this photomicrograph shows macrophages and giant cells in a case of xanthogranulomatous...

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Major prion protein

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CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85...

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List of distinct cell types in the adult human body

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Uterus None None unknown None IL1B, CD68 uterine macrophage unknown unknown placenta None None unknown None CD68, ITGAX, CD209, MRC1 uterine natural killer...

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PTPRC

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CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85...

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Glycoprotein Ib

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CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85...

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CD34

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CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85...

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Kounis syndrome

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by resident mononuclear cells in the substantia propria, which consist of CD68+ macrophages and monocytes. Kounis syndrome is often missed or underdiagnosed...

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