Proxibarbital information

Proxibarbital
Clinical data
Other names	Proxibarbital, Centralgol, Ipronal, 5-Allyl-5-(β-hydroxypropyl)barbituric acid
ATC code	N05CA22 (WHO) ;
Identifiers
	IUPAC name (RS)-5-allyl-5-(2-hydroxypropyl)pyrimidine-2,4,6(1H,3H,5H)-trione;
CAS Number	2537-29-3 ;
PubChem CID	17336;
ChemSpider	16406 ;
UNII	F97OMS297F;
ChEMBL	ChEMBL2105233;
CompTox Dashboard (EPA)	DTXSID20862980 ;
ECHA InfoCard	100.018.004
Chemical and physical data
Formula	C10H14N2O4
Molar mass	226.232 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1NC(=O)NC(=O)C1(CC(O)C)C\C=C;
	InChI InChI=1S/C10H14N2O4/c1-3-4-10(5-6(2)13)7(14)11-9(16)12-8(10)15/h3,6,13H,1,4-5H2,2H3,(H2,11,12,14,15,16) ; Key:VNLMRPAWAMPLNZ-UHFFFAOYSA-N ;
	(what is this?) (verify)

Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956. It has anti-anxiety properties and is, in contrast to most barbiturates, almost without hypnotic action.^[1]

It was also used in the treatment of migraine headaches in a similar manner to butalbital.^[2]

Valofane isomerises to Proxibarbal in vivo.

^ Zajdel P, Kulig K, Zejc A (2008). Zejc A, Gorczyca M (eds.). Chemia leków, podręcznik dla studentów farmacji i farmaceutów [Drug chemistry, textbook for pharmacy students and pharmacists] (in Polish). Warszawa, Poland. ISBN 978-83-200-3652-7.{{cite book}}: CS1 maint: location missing publisher (link)
^ Sulman FG, Pfeifer Y, Tal E (December 1976). "[Migraine therapy by enzyme induction with proxibarbital]". Therapie der Gegenwart (in German). 115 (12): 2088–103. PMID 14412.

[1] Zajdel P, Kulig K, Zejc A (2008). Zejc A, Gorczyca M (eds.). Chemia leków, podręcznik dla studentów farmacji i farmaceutów [Drug chemistry, textbook for pharmacy students and pharmacists] (in Polish). Warszawa, Poland. ISBN 978-83-200-3652-7.{{cite book}}: CS1 maint: location missing publisher (link)

[2] Sulman FG, Pfeifer Y, Tal E (December 1976). "[Migraine therapy by enzyme induction with proxibarbital]". Therapie der Gegenwart (in German). 115 (12): 2088–103. PMID 14412.

Proxibarbital information

and 28 Related for: Proxibarbital information

Proxibarbital

Methaqualone

Alprazolam

Benzene

Nicotinamide

Isopropyl alcohol

Lorazepam

Barbiturate

Pentobarbital

Dichloromethane

Dihydrotestosterone

Cholesterol

Ivermectin

Diethyl ether

Ethchlorvynol

Testosterone

Diazepam

Chloral hydrate

Acetone

Progesterone

Zolpidem

Chloroform

Secobarbital

Fluoxetine

Clonazepam

Zopiclone

Nitric oxide

Carbamazepine