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Protein aggregation predictors information


Computational methods that use protein sequence and/ or protein structure to predict protein aggregation. The table below, shows the main features of software for prediction of protein aggregation

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Protein aggregation predictors

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Computational methods that use protein sequence and/ or protein structure to predict protein aggregation. The table below, shows the main features of...

Word Count : 2523

Protein aggregation

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In molecular biology, protein aggregation is a phenomenon in which intrinsically-disordered or mis-folded proteins aggregate (i.e., accumulate and clump...

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Amyloid

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amyloid protein structure is a different conformation from the one that the antibody recognizes. JUNQ and IPOD Proteopathy Protein aggregation predictors Sunde...

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Protein folding

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merely a reflection of the loss of protein homeostasis, the balance between synthesis, folding, aggregation and protein turnover. Recently the European Medicines...

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Protein tertiary structure

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of software for protein tertiary structure prediction can be found at List of protein structure prediction software. Protein aggregation diseases such as...

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Prion

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yeast, prionogenic proteins have a portable prion domain that is both necessary and sufficient for self-templating and protein aggregation. This has been...

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Protein phosphorylation

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of Ser129 is associated with the aggregation of the protein and further damage to the nervous system. The aggregation of phosphorylated α-Synuclein can...

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Intrinsically disordered proteins

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of disorder. Meta-predictors show a new concept, combining different primary predictors to create a more competent and exact predictor. Due to the different...

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Beta sheet

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presumably to avoid the "edge-to-edge" association between proteins that might lead to aggregation and amyloid formation. A very simple structural motif involving...

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Protein complex

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aggregation. The structure of proteins play a role in how the multiprotein complex assembles. The interfaces between proteins can be used to predict assembly...

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Heat shock protein

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of proper protein conformation (shape) and prevention of unwanted protein aggregation. By helping to stabilize partially unfolded proteins, HSPs aid in...

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Tau protein

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synaptic cell adhesion proteins, neuronal activity and other synaptic and non-synaptic mechanisms. The mechanism of tau aggregation is still not completely...

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Hypochlorous acid

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Sulfenic acids form disulfides with another protein sulfhydryl group, causing cross-linking and aggregation of proteins. Sulfinic acid and R−S(=O)2−OH derivatives...

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Huntingtin

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Huntingtin+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) The Huntingtin Protein and Protein Aggregation at HOPES :...

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Casein

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mammalian milk, comprising about 80% of the proteins in cow's milk and between 20% and 60% of the proteins in human milk. Sheep and cow milk have a higher...

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Binding immunoglobulin protein

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of newly synthesized proteins, binding to misfolded proteins to prevent protein aggregation, translocation of secretory proteins, and initiation of the...

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Pheromone

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referred to as an aggregation, whether consisting of one sex or both sexes. Male-produced sex attractants have been called aggregation pheromones, because...

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Amyloid beta

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Pinheiro TJ (October 2009). "Insight into early events in the aggregation of the prion protein on lipid membranes". Biochimica et Biophysica Acta (BBA) -...

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Ferritin

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growth and as a coating to prevent coagulation/aggregation between NPs. Using various sizes of protein shells, various sizes of NPs can be easily synthesized...

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Protein kinase C

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In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the...

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CCL2

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Theoharides TC (November 1995). "Monocyte chemotactic protein-1 provokes mast cell aggregation and [3H]5HT release". Immunology. 86 (3): 434–40. PMC 1383948...

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Michele Vendruscolo

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noted for his theoretical and experimental work on protein folding, misfolding and aggregation. Vendruscolo is a graduate in physics of the University...

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Zinc finger

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A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) which stabilizes the fold...

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Hsp90

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shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation...

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GroEL

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succumb to a competing reaction, such as misfolding and aggregation with other misfolded proteins. The constricted nature of the interior of the molecular...

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Neurofilament

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IV intermediate filaments found in the cytoplasm of neurons. They are protein polymers measuring 10 nm in diameter and many micrometers in length. Together...

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Lattice protein

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Lattice proteins are highly simplified models of protein-like heteropolymer chains on lattice conformational space which are used to investigate protein folding...

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