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Beta sheet information


Three-dimensional structure of parts of a beta sheet in green fluorescent protein
Protein secondary structureBeta sheetAlpha helix
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The image above contains clickable links
Interactive diagram of hydrogen bonds in protein secondary structure. Cartoon above, atoms below with nitrogen in blue, oxygen in red (PDB: 1AXC​​)

The beta sheet (β-sheet, also β-pleated sheet) is a common motif of the regular protein secondary structure. Beta sheets consist of beta strands (β-strands) connected laterally by at least two or three backbone hydrogen bonds, forming a generally twisted, pleated sheet. A β-strand is a stretch of polypeptide chain typically 3 to 10 amino acids long with backbone in an extended conformation. The supramolecular association of β-sheets has been implicated in the formation of the fibrils and protein aggregates observed in amyloidosis, Alzheimer's disease and other proteinopathies.

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Beta sheet

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The beta sheet (β-sheet, also β-pleated sheet) is a common motif of the regular protein secondary structure. Beta sheets consist of beta strands (β-strands)...

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Supersecondary structure

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adjacent to, but not necessarily geometrically aligned with, each other. The beta sheet is anti-parallel, and alternate strands run in the same directions. The...

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Beta barrel

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In protein structures, a beta barrel (β barrel) is a beta sheetsheet) composed of tandem repeats that twists and coils to form a closed toroidal structure...

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Protein secondary structure

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most common secondary structural elements are alpha helices and beta sheets, though beta turns and omega loops occur as well. Secondary structure elements...

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Beta hairpin

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(the N-terminus of one sheet is adjacent to the C-terminus of the next), and linked by a short loop of two to five amino acids. Beta hairpins can occur in...

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Amyloid beta

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Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with...

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Silk

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Silk fibroin contains hydrophobic beta sheet blocks, interrupted by small hydrophilic groups. And the beta-sheets contribute much to the high mechanical...

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Rossmann fold

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alternating beta strands and alpha helical segments where the beta strands are hydrogen bonded to each other forming an extended beta sheet and the alpha...

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Beta bulge

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A beta bulge can be described as a localized disruption of the regular hydrogen bonding of beta sheet by inserting extra residues into one or both hydrogen...

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Protein contact map

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adjacent to the diagonal. Antiparallel beta sheets appear in HB plot as cross-diagonal. Parallel beta sheets appears in the HB plot as parallel to the...

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Amyloidosis

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proteins aggregate into distinctive fibrillar forms with a beta-sheet structure. The beta-sheet form of amyloid is proteolysis-resistant, meaning it can...

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Linus Pauling

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biological molecules, and showed the importance of the alpha helix and beta sheet in protein secondary structure. Pauling's approach combined methods and...

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List of proteins

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consisting of alpha helices), all beta proteins (domains consisting of beta sheets), and mixed alpha helix/beta sheet proteins. While most proteins adopt...

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Protein folding

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of secondary structure are the structures known as alpha helices and beta sheets that fold rapidly because they are stabilized by intramolecular hydrogen...

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LSm

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superfamilies, and folds. The LSm protein structure is an example of a small beta sheet folded into a short barrel. Individual LSm proteins assemble into a six...

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Alpha sheet

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Corey in 1951. The hydrogen bonding pattern in an alpha sheet is similar to that of a beta sheet, but the orientation of the carbonyl and amino groups in...

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Beta particle

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A beta particle, also called beta ray or beta radiation (symbol β), is a high-energy, high-speed electron or positron emitted by the radioactive decay...

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Interleukin

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beta and IL-1 receptor antagonist). The crystal structures of IL1A and IL1B have been solved, showing them to share the same 12-stranded beta-sheet structure...

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Protein structure prediction

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a likely helix may still be able to adopt a beta-strand conformation if it is located within a beta-sheet region of the protein and its side chains pack...

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ATPase

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Importantly, while all natural ATPases have some beta-sheet structure, the designed "Alternative ATPase" lacks beta sheet structure, demonstrating that this life-essential...

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Alpha helix

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steel, including ubiquitin and a potassium channel tetramer. 310 helix Beta sheet Davydov soliton Folding (chemistry) Knobs into holes packing Pi helix...

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