Not to be confused with Polypropylene glycol, Ethylene glycol, or Polyethylene glycol.
This article is about 1,2-propanediol. For other propylene glycols, see Propanediol.
Propylene glycol[1]
ball-and-stick model
Space-filling model
Names
Preferred IUPAC name
Propane-1,2-diol
Other names
Propylene glycol
α-Propylene glycol
1,2-Propanediol
1,2-Dihydroxypropane
Methyl ethyl glycol
Methylethylene glycol
Identifiers
CAS Number
57-55-6 racemicY
4254-15-3 S-enantiomer
3D model (JSmol)
Interactive image
ChEBI
CHEBI:16997Y
ChEMBL
ChEMBL286398Y
ChemSpider
13835224Y
ECHA InfoCard
100.000.307
EC Number
200-338-0
E number
E1520 (additional chemicals)
KEGG
C00583
PubChem CID
1030
RTECS number
TY6300000
UNII
6DC9Q167V3Y
942194N4TD (S-enantiomer)Y
CompTox Dashboard (EPA)
DTXSID0021206
InChI
InChI=1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3Y
Key: DNIAPMSPPWPWGF-UHFFFAOYSA-NY
SMILES
CC(O)CO
Properties
Chemical formula
C3H8O2
Molar mass
76.095 g·mol−1
Appearance
colourless liquid
Odor
odorless
Density
1.036 g/cm3
Melting point
−59 °C (−74 °F; 214 K)
Boiling point
188.2 °C (370.8 °F; 461.3 K)
Solubility in water
Miscible
Solubility in ethanol
Miscible
Solubility in diethyl ether
Miscible
Solubility in acetone
Miscible
Solubility in chloroform
Miscible
log P
-1.34[2]
Thermal conductivity
0.34 W/m-K (50% H2O @ 90 °C (194 °F))
Viscosity
0.042 Pa·s
Pharmacology
ATCvet code
QA16QA01 (WHO)
Hazards
NFPA 704 (fire diamond)
0
1
0
Related compounds
Related glycols
Ethylene glycol, 1,3-propanediol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Chemical compound
Propylene glycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Its chemical formula is CH3CH(OH)CH2OH.
As it contains two alcohol groups, it is classed as a diol. It is miscible with a broad range of solvents, including water, acetone, and chloroform. In general, glycols[5] are non-irritating and have very low volatility.[6]
It is produced on a large scale primarily for the production of polymers. In the European Union, it has E-number E1520 for food applications. For cosmetics and pharmacology, the number is E490. Propylene glycol is also present in propylene glycol alginate, which is known as E405. Propylene glycol is a compound which is GRAS (generally recognized as safe) by the US Food and Drug Administration under 21 CFR x184.1666, and is also approved by the FDA for certain uses as an indirect food additive. Propylene glycol is approved and used as a vehicle for topical, oral, and some intravenous pharmaceutical preparations in the U.S. and in Europe.
^The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals. Merck & Co. 1989. ISBN 978-0911910285.
^"Propylene Glycol_msds".
^GHS: "Kein gefährlicher Stoff nach GHS" GESTIS 013620
^"Propylene Glycol - Cameo Chemicals". NOAA Office of Response and Restoration. NOAA. Retrieved 3 October 2018.
^Zapka, Maskrey (2016). Hawaii Energy and Environmental Technologies (HEET) Initiative.
^Sullivan, Carl J.; Kuenz, Anja; Vorlop, Klaus-Dieter (2018). "Propanediols". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a22_163.pub2. ISBN 978-3527306732.
Propyleneglycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Its chemical...
is ethylene glycol or propyleneglycol. For ethylene glycol, the mixing ratios are typically 30/70 and 35/65, whereas the propyleneglycol mixing ratios...
Propyleneglycol methyl ether (PGME or 1-methoxy-2-propanol) is an organic solvent with a wide variety of industrial and commercial uses. Similar to other...
Propyleneglycol alginate (PGA) is an emulsifier, stabilizer, and thickener used in food products. It is a food additive with E number E405. Chemically...
are mixtures of water and either ethylene glycol (EGW) or propyleneglycol (PGW). The use of ethylene glycol has a longer history, especially in the automotive...
Propyleneglycol methyl ether acetate (PGMEA, 1-methoxy-2-propanol acetate) is a P-type glycol ether used in inks, coatings, and cleaners. It is sold by...
Glycol ethers are a class of chemical compounds consisting of alkyl ethers that are based on glycols such as ethylene glycol or propyleneglycol. They...
ester derived from propylene glycol. This colorless and odorless liquid is useful as a polar, aprotic solvent. Propylene carbonate is chiral, but is used...
Propyleneglycol dinitrate (PGDN, 1,2-propyleneglycol dinitrate, or 1,2-propanediol dinitrate) is an organic chemical, an ester of nitric acid and propylene...
Polypropylene glycol or polypropylene oxide is the polymer (or macromolecule) of propyleneglycol. Chemically it is a polyether, and, more generally speaking...
polypropylene glycol, propyleneglycol ethers, and propylene carbonate. The United States Food and Drug Administration has approved the use of propylene oxide...
Ethylene glycol and its ethers are nephrotoxic if applied to damaged skin. Ethylene Propyleneglycol Monoethylene glycol Diethylene glycol PEGylation...
Polyethylene glycolpropyleneglycol cocoates or PEG propyleneglycol cocoates are chemical compounds produced by the esterification of polyoxyalkyl alcohols...
is in beverage production, wherein the food grade chemical propyleneglycol is used. Glycol chillers are a specific kind of refrigeration system, often...
a variety of types, and are typically composed of ethylene glycol (EG) or propyleneglycol (PG), along with other ingredients such as thickening agents...
ethylene glycol. Examples of diols in which the hydroxyl functional groups are more widely separated include 1,4-butanediol HO−(CH2)4−OH and propylene-1,3-diol...
of propyleneglycol and glycerin is probably low. Propyleneglycol and glycerin have not been shown to be safe. Some research states that propylene glycol...
is a monopropellant mixture of chiefly propyleneglycol dinitrate (an ester of nitric acid and propyleneglycol, and structurally similar to nitroglycerin)...
the aerosol that delivers nicotine to the user. Like ethylene glycol and propyleneglycol, glycerol is a non-ionic kosmotrope that forms strong hydrogen...
produce aerosol between puffs. The e-cigarette aerosol usually contains propyleneglycol, glycerin, nicotine, flavors, aroma transporters, and other substances...
acidic catalysts. This type of process usually requires higher-purity propylene (> 90%). Direct hydration is more commonly used in Europe. Isopropyl alcohol...
properties of diethylene glycol make it an excellent counterfeit for pharmaceutical-grade glycerine (also called glycerol) or propyleneglycol, and has caused...
seen following the consumption of foods containing thiosulfate and propyleneglycol compounds by cats, dogs and certain primates. They are named after...
glycols (alcohols containing at least two hydroxyl groups), such as ethylene glycol [citation needed], propyleneglycol and glycerol. Ethylene glycol...
current causes of anion gap metabolic acidosis: G — glycols (ethylene glycol & propyleneglycol) O — oxoproline, a metabolite of paracetamol (acetaminophen)...
polyethylene glycol 400 and propyleneglycol. As a preservative, the injectable solution contains benzyl alcohol. Toxicity from propyleneglycol has been...
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