A prolactin modulator is a drug which affects the hypothalamic–pituitary–prolactin axis (HPP axis) by modulating the secretion of the pituitary hormone prolactin from the anterior pituitary gland. Prolactin inhibitors suppress and prolactin releasers induce the secretion of prolactin, respectively.[1][2]
^Thomas L. Lemke; David A. Williams (24 January 2012). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 432–. ISBN 978-1-60913-345-0.
^University of Kansas School of Nursing Karen Wambach (15 August 2014). Breastfeeding and Human Lactation. Jones & Bartlett Publishers. pp. 182–. ISBN 978-1-4496-9729-7.
and 25 Related for: Prolactin modulator information
A prolactinmodulator is a drug which affects the hypothalamic–pituitary–prolactin axis (HPP axis) by modulating the secretion of the pituitary hormone...
levels of prolactin in the blood. Normal levels average to about 13 ng/mL in women, and 5 ng/mL in men, with an upper normal limit of serum prolactin levels...
hetorodimers in vitro (and possibly in vivo) with DRD3, DRD5, and 5-HT2A. Prolactinmodulator D2sh–TAAR1 is a presynaptic heterodimer which involves the relocation...
like gastroparesis (delayed gastric emptying). It raises the level of prolactin in the human body and is used off label to induce and promote breast milk...
selective estrogen receptor modulators (SERMs). Despite its widespread use, the term "selective androgen receptor modulator" has been criticized by some...
supplies the pituitary gland. The prolactin cells that produce prolactin, in the absence of dopamine, secrete prolactin continuously; dopamine inhibits...
in the cortex influences the secretion of releasing hormones; GHRH and prolactin are stimulated whilst TRH is inhibited. The hypothalamus is responsive...
potent agonist of the prolactin receptor and a weak agonist of the growth hormone receptor. hPL has been found to bind to the prolactin receptor with equal...
a steroidal drug described as an antiprogestogen and "antiprolactin" (prolactin inhibitor). It was studied for lactation inhibition in bitches. It has...
among others, is a dopaminergic medication used in the treatment of high prolactin levels, prolactinomas, Parkinson's disease, and for other indications...
prolactin levels, body weight, and blood pressure. If prolactin levels are greater than 100 ng/mL, estrogen therapy should be stopped and prolactin levels...
and from there it is able to modulate the release of prolactin secretion. Once secreted from the pituitary gland, prolactin can increase many behaviors...
prolactin in the pituitary gland in lactating rats and lactating sheep. Administration of a solution of salsolinol was not shown to raise prolactin levels...
factors), the most important of which include estrogen, progesterone, prolactin, and growth hormone. The master regulators of breast development are the...
deficiency in the serum levels of the hypothalamic-pituitary hormone prolactin. Hypoprolactinemia is associated with ovarian dysfunction in women, and...
placental lactogen) genes. GH, human chorionic somatomammotropin, and prolactin belong to a group of homologous hormones with growth-promoting and lactogenic...
or who are pregnant. Clomifene is in the selective estrogen receptor modulator (SERM) family of medication and is a nonsteroidal medication. It works...
Rarely, CPA can produce blood clots, liver damage, excessively high prolactin levels, prolactinomas, and meningiomas. Upon discontinuation from high...
typical finding, but may be seen in a gynecomastic individual with a prolactin secreting tumor. An increase in the diameter of the areola and asymmetry...
release. Prolactin promotes milk production in human females. Its secretion is prompted by prolactin-releasing hormone and inhibited by prolactin-inhibiting...
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