Probenecid, also sold under the brand name Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia.
Probenecid was developed as an alternative to caronamide[1] to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and prolonging their effects.
^Mason RM (June 1954). "Studies on the effect of probenecid (benemid) in gout". Annals of the Rheumatic Diseases. 13 (2): 120–130. doi:10.1136/ard.13.2.120. PMC 1030399. PMID 13171805.
Probenecid, also sold under the brand name Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating...
particular allopurinol and Febuxostat, and uricosuric agents, such as probenecid and benzbromarone. Induction therapy of gout targets to relieve acute...
Probenecid with colchicine is a combination medication used to treat gout. Brand names include ColBenemid, Col-Probenecid, and Proben-C. "ColBenemid -...
Colchicine is a medication used to prevent and treat gout, to treat familial Mediterranean fever and Behçet's disease, and to reduce the risk of myocardial...
given concurrently with probenecid it is advised that drugs that are known to interact with probenecid (e.g. drugs that probenecid interferes with the renal...
lifestyle changes and in those with frequent attacks, allopurinol or probenecid provides long-term prevention. Taking vitamin C and having a diet high...
increase uric acid elimination from the body through the kidneys (e.g., probenecid), this can be referred to as refractory chronic gout (RCG). They are more...
necessary.[citation needed] Excretion of cephalosporins is reduced by probenecid (resulting in increased concentrations of drug in the blood plasma).[citation...
drugs (such as salicylates), sulfonamides, chloramphenicol, coumadin and probenecid may potentiate the hypoglycemic action of glimepiride. Thiazides, other...
eighteen Grand Tours. Delgado tested positive for the known masking agent Probenecid during the 1988 tour. The drug, which had been placed on the International...
uricosuric drug. By their mechanism of action, some uricosurics (such as probenecid) increase the blood plasma concentration of certain other drugs and their...
retained. The uricosuric agent probenecid proved to be suitable. When probenecid and penicillin are administered together, probenecid competitively inhibits the...
other β-lactam antibiotics, renal excretion of cefalexin is delayed by probenecid. It is also not recommended to take cefalexin with dofetilide, live Cholera...
(chemotherapy and immunosuppressant). Typhoid, Cholera and BCG vaccines. Probenecid reduces renal excretion and increases blood levels of amoxicillin. Oral...
four hours for 10 to 14 days. One daily intramuscular injection and oral probenecid four times daily, both for 10 to 14 days. Follow-up blood tests are generally...
or later in pregnancy. Ketorolac can interact with other medications. Probenecid can increase the probability of having an adverse reaction when taken...
NSAIDs. Naproxen may interact with antidepressants, lithium, methotrexate, probenecid, warfarin and other blood thinners, heart or blood pressure medications...
studies need to be done to evaluate the true potential of this synergy. Probenecid: Reports of increased half life of aciclovir, as well as decreased urinary...
flucloxacillin in the blood may rise in kidney failure and with the use of probenecid. Flucloxacillin is a narrow-spectrum antibiotic belonging to the penicillin...
to both allopurinol, a non-uricosuric xanthine oxidase inhibitor, and probenecid, another uricosuric drug. Benzbromarone is a very potent inhibitor of...
effects of the contraceptive. When probenecid is used concurrently with penicillin, kidney excretion of probenecid is decreased resulting in higher blood...
taken. Some important drugs that may interact with cefazolin such as probenecid. Side effects associated with use of cefazolin therapy include: Common...
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