Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication.[1] It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock itch.[1] It can be taken by mouth or applied as a cream to the skin or in the vagina.[1]
Common side effects when taken by mouth include nausea and itchiness.[1] When applied to the skin, common side effects include redness and a burning sensation.[1] In pregnancy, use on the skin or in the vagina is believed to be safe.[1] There is no evidence of harm when used by mouth during pregnancy but this has been less well studied.[1] When used by mouth, greater care should be taken in those with liver problems.[1] It is in the azole class of medications and works by disrupting the fungal cell membrane.[1]
Clotrimazole was discovered in 1969.[2] It is on the World Health Organization's List of Essential Medicines.[3] It is available as a generic medication.[1] In 2021, it was the 273rd most commonly prescribed medication in the United States, with more than 900,000 prescriptions.[4][5]
^ abcdefghijAmerican Society of Health-System Pharmacists (8 February 2016). "Clotrimazole Monograph for Professionals". www.drugs.com. Archived from the original on 28 October 2016. Retrieved 28 October 2016.
^Walker SR (2012). Trends and Changes in Drug Research and Development. Springer Science & Business Media. p. 109. ISBN 9789400926592. Archived from the original on 14 September 2016.
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
^"The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
^"Clotrimazole - Drug Usage Statistics". ClinCalc. Archived from the original on 18 January 2024. Retrieved 14 January 2024.
Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush...
used for is candida vulvovaginitis which is treated with intravaginal Clotrimazole This is sometimes indicated when there's a fungal infection on the skin...
lanosterol into ergosterol. Common examples of azole antifungals include clotrimazole, econazole, ketoconazole, miconazole, and tioconazole. The only polyene...
anti-inflammatory properties. Other topical antifungal agents such as clotrimazole, miconazole, terbinafine, or zinc pyrithione can lessen symptoms in some...
personal items. Treatment is typically with antifungal creams such as clotrimazole or miconazole. If the scalp is involved, antifungals by mouth such as...
betamethasone dipropionate, clotrimazole) contains both a corticosteroid (betamethasone) and anti-fungal agent (clotrimazole) and is used to treat fungal...
interfering with DNA activities. A number of substituted imidazoles, including clotrimazole, are selective inhibitors of nitric oxide synthase, which makes them...
foot and vaginal infections, isoconazole has a similar effectiveness to clotrimazole. Isoconazole nitrate may be used in combination with corticosteroid diflucortolone...
properties are similar to other azole fungicides such as ketoconazole, clotrimazole and miconazole. It is most commonly found as an active ingredient in...
needed] In the United States and Canada, betamethasone is mixed with clotrimazole and sold as Lotrisone and Lotriderm. It is also available in combination...
with an antifungal medication. This may be either as a cream such as clotrimazole or with oral medications such as fluconazole. Despite the lack of evidence...
Marbo vet and Zeniquin. A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available under the name Aurizon (CAS number 115550-35-1)...
vaginal infections. For infections of the mouth, treatment with topical clotrimazole or nystatin is usually effective. Oral or intravenous fluconazole, itraconazole...
treatment option for mixed infectious vaginitis is a combination of clotrimazole and metronidazole. The 5-nitroimidazole drugs (metronidazole and tinidazole)...
mometasone furoate and clotrimazole and gentamicin for veterinary use as Mometamax and Mometavet mometasone furoate and clotrimazole and mupirocin as Derma...
treatment option for mixed infectious vaginitis is a combination of clotrimazole and metronidazole. Vulvovaginitis in children may be "nonspecific", or...
are a quicker but more expensive form of treatment compared to azoles (clotrimazole, econazole, ketoconazole, oxiconazole, miconazole, sulconazole). If the...
Example of these medications include clindamycin, terconazole, miconazole, clotrimazole, when used as a vaginal cream or vaginal suppository, as well as butoconazole...
such as tinea capitis, doctors may recommend a treatment application of clotrimazole (commonly prescribed for jock itch or athlete's foot) or miconazole (commonly...
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