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Hypericum perforatum information


Hypericum perforatum
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Rosids
Order: Malpighiales
Family: Hypericaceae
Genus: Hypericum
Section: Hypericum sect. Hypericum
Species:
H. perforatum
Binomial name
Hypericum perforatum
L.
Subspecies
  • H. p. ssp. perforatum
  • H. p. ssp. songaricum
    (Ledeb. ex Rchb.) N.Robson
  • H. p. ssp. veronense
    (Ledeb. ex Rchb.) N.Robson
  • H. p. ssp. chinense
    (Schrank) H.Lindb.
Synonyms
  • H. officinale Gaterau
  • H. officinarum Crantz
  • H. vulgare Lam.

Hypericum perforatum, commonly known as St John's wort, is a flowering plant in the family Hypericaceae. It is a perennial plant that grows up to one meter tall, with many yellow flowers that have clearly visible black glands around their edges, long stamens (male reproductive organs), and three pistils (female reproductive organs). Probably a hybrid between the closely related H. attenuatum and H. maculatum that originated in Siberia, the species is now found worldwide. It is native to temperate regions across Eurasia and North Africa, and has been introduced to East Asia, Australia, New Zealand, and parts of North and South America. In many areas where it is not native, H. perforatum is considered a noxious weed. It densely covers open areas to the exclusion of native plants, and is poor grazing material. As such, methods for biocontrol have been introduced in an attempt to slow or reverse the spread of the species.

The species produces numerous chemical compounds that are highly active. These chemicals are harmful to large animals, especially sheep, and help to deter herbivores from consuming the plant. Other chemicals in the plant, such as hypericin and hyperforin, have various uses in medicine. St John's wort has been used in traditional medicine since at least the first century AD, often as a cure-all or panacea. The oil from its glands can be extracted, or its above-ground parts can be ground into a powder called herba hyperici. In modern times, its use as an antidepressant has been the focus of numerous studies and clinical trials; however, the active ingredients can be very harmful or even lethal when taken alongside other medicines.

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Hypericum perforatum

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Hypericum perforatum, commonly known as St John's wort, is a flowering plant in the family Hypericaceae. It is a perennial plant that grows up to one meter...

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Hypericum

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distinguishing characteristic; for example, H. perforatum and Hypericum maculatum are easily confused save for H. perforatum having two lines and H. maculatum having...

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Hyperforin

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phytochemical produced by some of the members of the plant genus Hypericum, notably Hypericum perforatum (St John's wort). Hyperforin may be involved in the pharmacological...

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Hypericum calycinum

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, Başer, K. H. C., & Berberoĝlu, H. (1996). Effects of Hypericum perforatum L. and Hypericum calycinum L. extracts on the central nervous system in mice...

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Antileukotriene

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and pranlukast, and 5-lipoxygenase inhibitors, like zileuton and Hypericum perforatum, can be used to treat these diseases. They are less effective than...

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List of antidepressants

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Transmetil, Samyl) – cofactor in monoamine neurotransmitter biosynthesis Hypericum perforatum [St. John's Wort (SJW)] (Jarsin, Kira, Movina) – TRPC6 activator...

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Omeprazole

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to the more alkaline environment of the stomach. St. John's wort (Hypericum perforatum) and Ginkgo biloba significantly reduce plasma concentrations of...

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Hypericum androsaemum

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antidepressant activities of the Portuguese Hypericum foliosum, Hypericum androsaemum and Hypericum perforatum medicinal plants". Industrial Crops and Products...

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Hypericum maculatum

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hybridises with Hypericum perforatum to produce Des Etang's St John's wort, Hypericum x desetangsii. It is considered to be a medicinal plant. Hypericum maculatum...

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Root beer

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species – mint carbonated water Hordeum vulgare – barley (malted) Hypericum perforatum – St. John's wort sugar molasses yeast Drink portal Philadelphia...

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Pseudohypericin

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most commonly in the St. John's wort family of plants, namely in Hypericum perforatum. In preliminary studies in animal models, pseudohypericin has shown...

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Exodermis

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bioactive constituents that are found to accumulate in the root system Hypericum perforatum. Xanthones are abundant in angiosperms with cDNA evidence suggesting...

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Hypericin

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Regulation of Hypericin synthesis via the Polyketide Pathway in Hypericum perforatum and Experimental Methods Proposed to Evaluate the Hypothesis". Archived...

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Nevirapine

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nevirapine levels.[18] In addition, concomitant use of St. John's wort (Hypericum perforatum, which has been shown to induce CYP3A4 and CYP1A2) or St. John's...

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Herb

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types of herbal extract, such as the extract of St. John's-wort (Hypericum perforatum) or of kava (Piper methysticum) can be used for medical purposes...

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List of Hypericum species

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PMID 22593920 "Species: Hypericum perforatum". www.fs.fed.us. Retrieved 2018-12-18. Oterino, A.; Lainz, M. (1997). "Sobre Hypericum tetrapterum Fr. e H....

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Fenbendazole

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Griseofulvin Guggulsterone Haloprogin Hetacillin potassium Hyperforin Hypericum perforatum (St John's wort) Indinavir sulfate Lasalocid sodium Levothyroxine...

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Atypical antidepressant

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Ademetionine (SAMe) GABAkine neurosteroids (brexanolone, zuranolone) Hypericum perforatum (St. John's Wort) Oxitriptan (5-HTP) Rubidium chloride (RbCl) Tryptophan...

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Agrilus hyperici

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agent of biological pest control against common St. John's wort (Hypericum perforatum) in areas where it is a noxious weed or invasive species. The adult...

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Flucloxacillin

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Griseofulvin Guggulsterone Haloprogin Hetacillin potassium Hyperforin Hypericum perforatum (St John's wort) Indinavir sulfate Lasalocid sodium Levothyroxine...

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Rifaximin

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Griseofulvin Guggulsterone Haloprogin Hetacillin potassium Hyperforin Hypericum perforatum (St John's wort) Indinavir sulfate Lasalocid sodium Levothyroxine...

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Fentanyl

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Griseofulvin Guggulsterone Haloprogin Hetacillin potassium Hyperforin Hypericum perforatum (St John's wort) Indinavir sulfate Lasalocid sodium Levothyroxine...

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Chrysolina quadrigemina

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Suffrian in 1851. It is native to Europe and North Africa. It feeds on Hypericum perforatum and other members of the genus. This plant is an introduced invasive...

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Amitriptyline

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metabolites on comedication with an extract from St. John's wort ( Hypericum perforatum )". Journal of Clinical Psychopharmacology. 22 (1): 46–54. doi:10...

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Antidepressant

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1016/S1043-6618(02)00266-9. PMID 12543057. Nathan PJ (March 2001). "Hypericum perforatum (St John's Wort): a non-selective reuptake inhibitor? A review of...

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Cypermethrin

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Griseofulvin Guggulsterone Haloprogin Hetacillin potassium Hyperforin Hypericum perforatum (St John's wort) Indinavir sulfate Lasalocid sodium Levothyroxine...

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Chrysolina

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them have been used for biological control of weeds. To control Hypericum perforatum (St John's wort), C. hyperici was successfully naturalized in Australia...

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