Pocket protein family information

Pocket protein family consists of three proteins: RB – Retinoblastoma protein p107 – Retinoblastoma-like protein 1 p130 – Retinoblastoma-like protein...

belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins. Should an oncogenic protein, such as those...

expression of genes necessary for G0 exit. Other members of the Rb pocket protein family, such as p107 and p130, have also been found to be involved in G0...

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions...

kilodalton heat shock proteins (Hsp70s or DnaK) are a family of conserved ubiquitously expressed heat shock proteins. Proteins with similar structure...

factors (ARFs) are members of the ARF family of GTP-binding proteins of the Ras superfamily. ARF family proteins are ubiquitous in eukaryotic cells, and...

challenging and exciting topic. Unlike globular proteins, IDPs do not have spatially-disposed active pockets. Fascinatingly, 80% of target-unbound IDPs (~4...

complexes with the pocket proteins. pRb is one of the targets of the oncogenic human papilloma virus protein E7, and human adenovirus protein E1A. By binding...

shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation...

the integral membrane proteins appear to have evolved independently several times, and thus comprise different protein families. Like the ABC exporters...

DREAM complex might enhance anticancer treatments such as imatinib. Pocket protein family Sadasivam, Subhashini; DeCaprio, James A. (11 July 2013). "The DREAM...

In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA...

case, PRCs have two related proteins (L/M; D1/D2; PsaA/PsaB) making up a quasi-symmetrical 5-helical core complex with pockets for pigment binding. The two...

In molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest...

a family of related proteins that are expressed in all animal cell lineages and organs. All Ras protein family members belong to a class of protein called...

(binding to) extracellular molecules. They are specialized integral membrane proteins that allow communication between the cell and the extracellular space....

successful proteins, ignoring the possibility of a perfectly druggable, but yet undrugged protein family; and (2) assumes that all protein family members...

proteins form a characteristic glove shape, encompassing a ligand-binding pocket that accommodates specific small organic chemicals. Urinary proteins...

A bromodomain is an approximately 110 amino acid protein domain that recognizes acetylated lysine residues, such as those on the N-terminal tails of histones...

buried in a protein's hydrophobic binding pocket after dissociation from the membrane. This process occurs within the beta-subunits of G-proteins. Perhaps...

Streptavidin /ˌstrɛpˈtævɪdɪn/ is a 52 kDa protein (tetramer) purified from the bacterium Streptomyces avidinii. Streptavidin homo-tetramers have an extraordinarily...

mammals weighing less than 5 kilograms (11 lb). The term "pocket pet" is used for a small, pocket-sized mammal (sometimes also categorized as a "small and...

Members of the signal transducer and activator of transcription (STAT) protein family are intracellular transcription factors that mediate many aspects of...