Piroctone olamine information

Piroctone olamine
Identifiers
CAS Number	68890-66-4 ;
3D model (JSmol)	Interactive image;
ChemSpider	45574 ;
ECHA InfoCard	100.065.957
MeSH	Piroctone+olamine
PubChem CID	50258;
UNII	A4V5C6R9FB ;
CompTox Dashboard (EPA)	DTXSID4046735 ;
	InChI InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2 Key: BTSZTGGZJQFALU-UHFFFAOYSA-N ; InChI=1/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2 Key: BTSZTGGZJQFALU-UHFFFAOYAP;
	SMILES CC1=CC(=O)N(C(=C1)CC(C)CC(C)(C)C)O.C(CO)N;
Properties
Chemical formula	C16H30N2O3
Molar mass	298.421
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Piroctone olamine (INN; also known as piroctone ethanolamine) is a compound sometimes used in the treatment of fungal infections.^[1] Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone was first synthesized in 1979 by Schwarzkopf-Henkel (Germany).

It is often used in anti-dandruff shampoo as a replacement for the commonly used compound zinc pyrithione which was banned in the EU in 2021 because of concerns for environmental toxicity.

It is structurally similar to ciclopirox and pyrithione, containing a substituted pyridine (pyridinone) group which inhibits ergosterol synthesis.^{[citation needed]}

^ Dubini F, Bellotti MG, Frangi A, Monti D, Saccomani L (2005). "In vitro antimycotic activity and nail permeation models of a piroctone olamine containing transungual water soluble technology". Arzneimittel-Forschung. 55 (8): 478–83. doi:10.1055/s-0031-1296892. PMID 16149717. S2CID 11337188.

[pmid16149717-1] Dubini F, Bellotti MG, Frangi A, Monti D, Saccomani L (2005). "In vitro antimycotic activity and nail permeation models of a piroctone olamine containing transungual water soluble technology". Arzneimittel-Forschung. 55 (8): 478–83. doi:10.1055/s-0031-1296892. PMID 16149717. S2CID 11337188.

Piroctone olamine information

and 26 Related for: Piroctone olamine information

Piroctone olamine

Dandruff

Ketoconazole

Antifungal

Management of hair loss

Malassezia furfur

Dupilumab

Zinc pyrithione

Cromoglicic acid

Oxymetazoline

Keratolytic

Tacrolimus

Minoxidil

Seborrhoeic dermatitis

Monobenzone

Hydroquinone

Dutasteride

Abrocitinib

Tralokinumab

Metandienone

Hyaluronic acid

Hydrogen peroxide

Finasteride

Diclofenac

Hair removal

Crisaborole

Identifiers

CAS Number	68890-66-4^Y
3D model (JSmol)	Interactive image
ChemSpider	45574^N
ECHA InfoCard	100.065.957
MeSH	Piroctone+olamine
PubChem CID	50258
UNII	A4V5C6R9FB^Y
CompTox Dashboard (EPA)	DTXSID4046735
InChI InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2^N Key: BTSZTGGZJQFALU-UHFFFAOYSA-N^N InChI=1/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2 Key: BTSZTGGZJQFALU-UHFFFAOYAP
SMILES CC1=CC(=O)N(C(=C1)CC(C)CC(C)(C)C)O.C(CO)N
Properties
Chemical formula	C₁₆H₃₀N₂O₃
Molar mass	298.421
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references