Nitrofurazone (INN, trade name Furacin) is an antimicrobial organic compound belonging to the nitrofuran class.[1] It is most commonly used as a topical antibiotic ointment.[2] It is effective against gram-positive bacteria, gram-negative bacteria, and can be used in the treatment of trypanosomiasis.[1][3][4] Its use in medicine has become less frequent, as safer and more effective products have become available.[5] Nitrofurazone is listed under California Prop 65, and has demonstrated clear evidence to be mutagenic and carcinogenic during animal studies, and has been discontinued for human use in the USA.[2][5][6][7] The substance is pale yellow and crystalline. It was once widely used as an antibiotic for livestock.[8][9]
^ abPerez S (26 May 2010). "Nitrofuran Analyses". Adpen Laboratories. Retrieved 14 March 2018.
^"Nitrofurazone". Office of Environmental Health Hazard Assessment. 2015-03-22. Retrieved 2018-03-14.
^National Toxicology Program (June 1988). "NTP Toxicology and Carcinogenesis Studies of Nitrofurazone in F344/N Rats and B6C3F1 Mice (Feed Studies)" (PDF). National Toxicology Program Technical Report Series. 337. NIH Publication No. 88-2593. National Institute of Health: 1–186.
^Vass M, Hruska K, Franek M (2008). "Nitrofuran antibiotics: a review on the application, prohibition and residual analysis". Veterinarni Medicina. 53 (9): 469–500. doi:10.17221/1979-VETMED.
^"Nitrofurazone Ointment for Animal Use - Drugs.com". Drugs.com. Retrieved 2018-03-14.
Nitrofurazone (INN, trade name Furacin) is an antimicrobial organic compound belonging to the nitrofuran class. It is most commonly used as a topical...
topical uses) in January 1992. The topical use of furazolidone and nitrofurazone was prohibited in 2002. Australia prohibited the use of nitrofurans...
Nifuroxazide Nifurquinazol Nifurtoinol Nifurzide Nitrofural (also known as nitrofurazone) Nitrofurantoin — a drug used to treat urinary tract infections Ranbezolid...
have the structure (CH3)2C=NNHC(=O)NH2. Some semicarbazones, such as nitrofurazone, and thiosemicarbazones are known to have anti-viral and anti-cancer...
against MuH strains. Other antibiotic agents, such as azelaic acid, nitrofurazone, silver sulfadiazine, and ramoplanin have been shown to be effective...
pharmaceuticals including nitrofuran antibacterials (furazolidone, nitrofurazone, nitrofurantoin) and related compounds. It is also a product of degradations...
Most Streptococcus milleri strains are resistant to bacitracin and nitrofurazone, and sulfonamides are totally ineffective. However, most strains studied...
FDA as mutagens/carcinogens, and can no longer be used as of 1991. Nitrofurazone Nitrofurantoin Norwich Pharmacal Co. & Others v Customs and Excise Commissioners...
Gram-negative, fish can be treated with a combination of the antibiotics nitrofurazone and kanamycin administered together synergistically. A medicated fish...
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